Thomas O'Loughlin

Icahn School of Medicine at Mount Sinai

United States

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Articles (6)

Year:

2025

Year:

2024

Year:

2024

Year:

2024

Year:

2022

Year:

2020

Collaborators (6)

James R Edgar

UNITED KINGDOM

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Abolfazl Arab

UNITED STATES

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Folma Buss

Professor in Molecular and Cellular Biology

University of Cambridge

UNITED KINGDOM

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Ziyang Zhang

Assistant Professor

UC Berkeley College of Chemistry

UNITED STATES

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Alan J Warren

University of Cambridge

UNITED KINGDOM

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Michael Geeves

Professor

University of Kent

UNITED KINGDOM

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Thomas O'Loughlin

Research Interests

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Articles (6)

Engineered CRISPR-Cas12a for higher-order combinatorial chromatin perturbations

Motor domain phosphorylation increases nucleotide exchange and turns MYO6 into a faster and stronger motor

Androgen receptor inhibition increases MHC Class I expression and improves immune response in prostate cancer

In vivo perturb-seq of cancer and microenvironment cells dissects oncologic drivers and radiotherapy responses in glioblastoma

IFITM proteins assist cellular uptake of diverse linked chemotypes

OPTN recruitment to a Golgi-proximal compartment regulates immune signalling and cytokine secretion.

Collaborators (6)

James R Edgar

Abolfazl Arab

Folma Buss

Ziyang Zhang

Alan J Warren

Michael Geeves

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