Thomas Poulsen

Professor

Aarhus University

Denmark

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Professors in Organic Chemistry

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About

Thomas Poulsen is a Professor at Aarhus University, Denmark. His research primarily focuses on organic chemistry, particularly in synthetic methodologies and the study of enzyme mechanisms. Recent publications include work on modular synthesis of lactams and investigations into polyether ionophore antibiotics, contributing to advancements in both chemical biology and medicinal chemistry.

Articles (18)

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2025

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2025

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2025

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2025

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2024

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2024

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2024

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2024

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2023

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2023

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2022

Collaborators (9)

Mogens Johannsen

Aarhus University

DENMARK

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Thomas Tørring

Aarhus University

DENMARK

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Hanne Ingmer

Københavns Universitet

DENMARK

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Jacob Seefeldt

Aarhus University

DENMARK

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Karl Anker Jørgensen

DENMARK

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Marta Gil-Ordóñez

Universitat Autònoma de Barcelona (UAB)

SPAIN

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Charlotte Held Gotfredsen

Technical University of Denmark

DENMARK

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Dennis Wilkens Juhl

Aarhus University

DENMARK

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Esben B. Svenningsen

Aarhus University

DENMARK

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Thomas Poulsen

Research Interests

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About

Articles (18)

Modular Synthesis of Substituted Lactams via a Deoxygenative Photochemical Alkylation–Cyclization Cascade of Secondary Amides in Flow

P450 Enzyme LyoI Performs Hydro‐2,2′‐Bifuran Oxidation in the Polyether Ionophore Lysocellin

P450 Enzyme LyoI Performs Hydro‐2,2′‐Bifuran Oxidation in the Polyether Ionophore Lysocellin

Total syntheses of cyclohelminthol I–IV reveal a new cysteine-selective covalent reactive group

Enantioselective Synthesis of α‐Quaternary Isochromanes by Oxidative Aminocatalysis and Gold Catalysis

Preparation and Preclinical Characterization of a Simple Ester for Dual Exogenous Supply of Lactate and Beta-hydroxybutyrate

An Enantioselective Aminocatalytic Cascade Reaction Affording Bioactive Hexahydroazulene Scaffolds

The Biological Activities of Polyether Ionophore Antibiotic Routiennocin is Independent of Absolute Stereochemistry

Polyether Ionophore Antibiotics Target Drug-Resistant Clinical Isolates, Persister Cells, and Biofilms

α‐Lactam Electrophiles for Covalent Chemical Biology**

α‐Lactam Electrophiles for Covalent Chemical Biology**

oxSTEF Reagents Are Tunable and Versatile Electrophiles for Selective Disulfide-Rebridging of Native Proteins

NRF2 activators inhibit influenza A virus replication by interfering with nucleo-cytoplasmic export of viral RNPs in an NRF2-independent manner

Triculamin

A stable α-lactam reagent for bioconjugation and proteomic profiling

Triculamin: An Unusual Lasso Peptide with Potent Antimycobacterial Activity

The [4.3.0] Piperidine Alkaloids: Architectures, Biology, Biosyntheses, and the Complete Details of the Asymmetric Syntheses of Streptazone A and Abikoviromycin

Forward Chemical Genetic Screen for Oxygen‐Dependent Cytotoxins Uncovers New Covalent Fragments that Target GPX4

Collaborators (9)

Mogens Johannsen

Thomas Tørring

Hanne Ingmer

Jacob Seefeldt

Karl Anker Jørgensen

Marta Gil-Ordóñez

Charlotte Held Gotfredsen

Dennis Wilkens Juhl

Esben B. Svenningsen

Make your next move.

Thomas Poulsen

Research Interests

Explore related searches

Contact this professor

About

Articles (18)

Modular Synthesis of Substituted Lactams via a Deoxygenative Photochemical Alkylation–Cyclization Cascade of Secondary Amides in Flow

P450 Enzyme LyoI Performs Hydro‐2,2′‐Bifuran Oxidation in the Polyether Ionophore Lysocellin

P450 Enzyme LyoI Performs Hydro‐2,2′‐Bifuran Oxidation in the Polyether Ionophore Lysocellin

Total syntheses of cyclohelminthol I–IV reveal a new cysteine-selective covalent reactive group

Enantioselective Synthesis of α‐Quaternary Isochromanes by Oxidative Aminocatalysis and Gold Catalysis

Preparation and Preclinical Characterization of a Simple Ester for Dual Exogenous Supply of Lactate and Beta-hydroxybutyrate

An Enantioselective Aminocatalytic Cascade Reaction Affording Bioactive Hexahydroazulene Scaffolds

The Biological Activities of Polyether Ionophore Antibiotic Routiennocin is Independent of Absolute Stereochemistry

Polyether Ionophore Antibiotics Target Drug-Resistant Clinical Isolates, Persister Cells, and Biofilms

α‐Lactam Electrophiles for Covalent Chemical Biology**

α‐Lactam Electrophiles for Covalent Chemical Biology**

oxSTEF Reagents Are Tunable and Versatile Electrophiles for Selective Disulfide-Rebridging of Native Proteins

NRF2 activators inhibit influenza A virus replication by interfering with nucleo-cytoplasmic export of viral RNPs in an NRF2-independent manner

Triculamin

A stable &alpha;-lactam reagent for bioconjugation and proteomic profiling

Triculamin: An Unusual Lasso Peptide with Potent Antimycobacterial Activity

The [4.3.0] Piperidine Alkaloids: Architectures, Biology, Biosyntheses, and the Complete Details of the Asymmetric Syntheses of Streptazone A and Abikoviromycin

Forward Chemical Genetic Screen for Oxygen‐Dependent Cytotoxins Uncovers New Covalent Fragments that Target GPX4

Collaborators (9)

Mogens Johannsen

Thomas Tørring

Hanne Ingmer

Jacob Seefeldt

Karl Anker Jørgensen

Marta Gil-Ordóñez

Charlotte Held Gotfredsen

Dennis Wilkens Juhl

Esben B. Svenningsen

Make your next move.

A stable α-lactam reagent for bioconjugation and proteomic profiling