Thomas R. Müller

Postdoctoral Fellow in T cell immunology and solid tumors at Karolinska Institutet This postdoctoral scholarship sits in the TRM Group led by Assistant Professor Thomas R. Müller at Karolinska Institutet, within the Center for Hematology and Regenerative Medicine (HERM) and the Department of Medicine Huddinge. The project focuses on fundamental human T cell biology in the context of solid tumors, with an initial emphasis on lung cancer, and aims to turn mechanistic insight into strategies for cellular immunotherapy. You will join a newly established and rapidly developing research team working in a small, collaborative setting alongside the PI, other postdocs, and PhD students. The group is described as international, interdisciplinary, and strongly supportive of scientific independence and career development. HERM provides a research environment focused on the human immune system in malignancy and immunodeficiency, together with access to state-of-the-art cell culture, molecular biology, flow cytometry, and microscopy facilities. The project is centered on how T cells move between the circulation and tumor tissue and how tissue-resident memory T cells contribute to anti-tumor immunity in lung cancer. You will use and adapt cutting-edge approaches established in the TRM Group to study antigen-specific T cell responses directly ex vivo, generate and analyze multi-omic datasets, and, where possible, help translate the findings into novel T cell engineering strategies. The work is positioned at the interface of tissue immunology, tumor biology, and translational cellular immunotherapy. The host institution is one of the world’s leading medical universities and offers a broad biomedical research environment with strong links to healthcare providers. The position is based at Karolinska South Campus, Flemingsberg.