Thomas Rando

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Professor

University of California

United States

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About

Professor Thomas Rando is a faculty member at the University of California, USA. His research focuses on muscle regeneration, brain aging, and the integration of biotechnology in health sciences. Recent articles authored by him explore diverse topics such as volumetric muscle loss, single-cell transcriptomics, and the impact of diet on tissue inflammation.

Recent Grants

Grant: Close

Epigenetic Reprogramming of Cellular Age

Open Date: 2021-05-01

Close Date: 2026-02-28

Grant: Close

Aging and Stem Cell Resilience

Open Date: 2021-04-01

Close Date: 2025-12-31

Grant: Close

Molecular Regulation of Stem Cell Quiescence

Open Date: 2018-04-01

Close Date: 2023-03-31

Grant: Close

TGF-beta family members and their binding proteins in aging skeletal muscle

Open Date: 2017-09-15

Close Date: 2021-05-31

Grant: Close

Complement Components as Mediators of Cell and Tissue Aging

Open Date: 2017-09-01

Close Date: 2022-05-31

Articles (17)

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2025

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2023

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2023

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2022

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2022

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2021

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2020

Collaborators (12)

Anja Groth

Københavns Universitet

DENMARK

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Sabrina Büttner

John J McCarthy

University of Kentucky

UNITED STATES

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Thomas Rando

Research Interests

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About

Recent Grants

Articles (17)

Spatial transcriptomic clocks reveal cell proximity effects in brain ageing

A mouse model of volumetric muscle loss and therapeutic scaffold implantation

Protocol for quantifying muscle fiber size, number, and central nucleation of mouse skeletal muscle cross-sections using Myotally software.

Brain aging and rejuvenation at single-cell resolution

Scanorama: integrating large and diverse single-cell transcriptomic datasets

Skeletal muscle-on-a-chip in microgravity as a platform for regeneration modeling and drug screening

Depletion of SAM leading to loss of heterochromatin drives muscle stem cell ageing

Hematologic DNMT3A reduction and high-fat diet synergize to promote weight gain and tissue inflammation.

Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity.

Erratum: Hematologic DNMT3A reduction and high-fat diet synergize to promote weight gain and tissue inflammation (iScience (2024) 27(3), (S2589004224003432), (10.1016/j.isci.2024.109122))

Division-Independent Differentiation of Muscle Stem Cells During a Growth Stimulus

Regulation of adult stem cell quiescence and its functions in the maintenance of tissue integrity

Ageing and rejuvenation of tissue stem cells and their niches

Scalable macroporous hydrogels enhance stem cell treatment of volumetric muscle loss

Tubastatin A maintains adult skeletal muscle stem cells in a quiescent state ex vivo and improves their engraftment ability in vivo

Cells, scaffolds, and bioactive factors: Engineering strategies for improving regeneration following volumetric muscle loss

Stem cell therapy for muscular dystrophies

Collaborators (12)

Anja Groth

Sabrina Büttner

Estéfano Pinilla

Rachel Rau

Alexandra Stolzing

Ling Liu

Fabian Finger

Sinjini Gupta

Di Wu

Vincenzo Sorrentino

Antoine de Morrée

John J McCarthy

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