thomas wileman

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Professor Molecular Virology

University of East Anglia

United Kingdom

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Thomas Wileman is a Professor of Molecular Virology at the University of East Anglia, UK. His research primarily focuses on autophagy and its role in viral infections, including the mechanisms by which various viruses manipulate host cellular processes. Recent publications highlight his work on the regulation of autophagy during viral infections and its implications for diseases such as Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Alzheimer's disease.

Recent Grants

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Gut Health anf Food Safety

Open Date: 2012-04-01

Close Date: 2017-03-01

Articles (12)

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2025

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2020

Collaborators (14)

David Criddle

Senior Lecturer

University of Liverpool

UNITED KINGDOM

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Ulrike Mayer

University of East Anglia

UNITED KINGDOM

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Craig McBeth

Teesside University

UNITED KINGDOM

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Tomoki Kuwahara

Assistant Professor

University of Tokyo

JAPAN

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Shen-Yuan Hsieh

Queen's University Belfast

UNITED KINGDOM

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Bradlee L. Heckmann

UNITED STATES

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Simon Carding

University of East Anglia

UNITED KINGDOM

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James Stewart

Professor

University of Liverpool

UNITED KINGDOM

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Derek T. Warren

UNITED KINGDOM

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Evelien Adriaenssens

Quadram Institute Bioscience

UNITED KINGDOM

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Penny Powell

Senior Lecturer

University of East Anglia

UNITED KINGDOM

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Raquel Villamuera

Instituto Nacional de Técnica Aerospacial

SPAIN

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Takeshi Iwatsubo

University of Tokyo

JAPAN

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Christopher Morris

University of East Anglia

UNITED KINGDOM

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thomas wileman

Research Interests

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Recent Grants

Articles (12)

Dynamic regulation of autophagy during Semliki Forest virus infection of neuroblastoma cells

Deletion of the WD40 domain of ATG16L1 exacerbates acute pancreatitis, abolishes LAP-like non-canonical autophagy and slows trypsin degradation

The WD Domain of Atg16l1 Crucial for LC3-Associated Phagocytosis Is Not Required for Preserving Skin Barrier Function in Mice

The V-ATPase–ATG16L1 axis recruits LRRK2 to facilitate the lysosomal stress response

Investigating the Human Intestinal DNA Virome and Predicting Disease-Associated Virus–Host Interactions in Severe Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)

Control of infection by LC3-associated phagocytosis, CASM, and detection of raised vacuolar pH by the V-ATPase-ATG16L1 axis

LC3-associated phagocytosis in bone marrow macrophages suppresses acute myeloid leukemia progression through STING activation

Autophagy impairment by African swine fever virus

Noncanonical function of an autophagy protein prevents spontaneous Alzheimer’s disease

Regulation of cytokine signaling through direct interaction between cytokine receptors and the ATG16L1 WD40 domain

Regulatory network analysis of Paneth cell and goblet cell enriched gut organoids using transcriptomics approaches.

The Uptake, Trafficking, and Biodistribution of Bacteroides thetaiotaomicron Generated Outer Membrane Vesicles.

Collaborators (14)

David Criddle

Ulrike Mayer

Craig McBeth

Tomoki Kuwahara

Shen-Yuan Hsieh

Bradlee L. Heckmann

Simon Carding

James Stewart

Derek T. Warren

Evelien Adriaenssens

Penny Powell

Raquel Villamuera

Takeshi Iwatsubo

Christopher Morris

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