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Tillie-Louise Hackett

Professor

The University of British Columbia

Canada

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Research Interests

Epidemiology

20%

Cardiology

20%

Inflammatory Biology

50%

Pulmonary Fibrosis

50%

Lung Disease

50%

Respiratory Medicine

40%

Bronchoscopy

30%

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Articles14

Effect of age, COPD severity and cigarette smoke exposure on bronchial epithelial barrier function

Article Link

Year:

2025

Extracellular Matrix Remodeling in Atopic Dermatitis Harnesses the Onset of an Asthmatic Phenotype and Is a Potential Contributor to the Atopic March.

Article Link

Year:

2024

Interleukin-1α inhibits transforming growth factor-β1 and β2-induced extracellular matrix production, remodeling and signaling in human lung fibroblasts: Master regulator in lung mucosal repair

Article Link

Year:

2024

Platelet Activating Factor Receptor and Intercellular Adhesion Molecule–1 Expression Increases in the Small Airway Epithelium and Parenchyma of Patients with Idiopathic Pulmonary Fibrosis: Implications for Microbial Pathogenesis

Article Link

Year:

2024

TGF-β1, pSmad-2/3, Smad-7, and β-Catenin Are Augmented in the Pulmonary Arteries from Patients with Idiopathic Pulmonary Fibrosis (IPF): Role in Driving Endothelial-to-Mesenchymal Transition (EndMT)

Article Link

Year:

2024

Taking Small Airways in Chronic Obstructive Pulmonary Disease to TASC

Article Link

Year:

2023

Hedgehog Signaling as a Therapeutic Target for Airway Remodeling and Inflammation in Allergic Asthma

Article Link

Year:

2022

The Role of the Dynamic Lung Extracellular Matrix Environment on Fibroblast Morphology and Inflammation

Article Link

Year:

2022

Reply to Cottin: Small Airways in Pulmonary Fibrosis: Revisiting an Old Question with New Tools

Article Link

Year:

2022

Angiotensin-Converting Enzyme 2 (ACE2), Transmembrane Peptidase Serine 2 (TMPRSS2), and Furin Expression Increases in the Lungs of Patients with Idiopathic Pulmonary Fibrosis (IPF) and Lymphangioleiomyomatosis (LAM): Implications for SARS-CoV-2 (COVID-19) Infections

Article Link

Year:

2022

Modeling Extracellular Matrix-Cell Interactions in Lung Repair and Chronic Disease

Article Link

Year:

2021

Pulmonary Vascular Remodeling Is an Early Feature of Fatal and Nonfatal Asthma

Article Link

Year:

2021

What Have In Vitro Co-Culture Models Taught Us about the Contribution of Epithelial-Mesenchymal Interactions to Airway Inflammation and Remodeling in Asthma?

Article Link

Year:

2020

Reply to Janssen and Wouters: Loss of Alveolar Attachments as a Pathomechanistic Link between Small Airway Disease and Emphysema

Article Link

Year:

2020

Collaborators12

Anne Voss

Freie Universität Berlin

GERMANY

Wim Timens

Scientific Staff, Professor

Universitair Medisch Centrum Groningen (UMCG)

NETHERLANDS

sathish venkatachalem

North Dakota State University

UNITED STATES

Emmanuel Twumasi Osei

Assistant Professor

University of British Columbia Okanagan

CANADA

Maor Sauler

Yale University

UNITED STATES

Susanne Lau

Senior Consultant, Professor

Charité - Universitätsmedizin Berlin

GERMANY

Honglin Luo

Professor

The University of British Columbia

CANADA

Sukhwinder Singh Sohal

AUSTRALIA

Leila Mostaço-Guidolin

Assistant Professor

Carleton University

CANADA

Chinten James Lim

Associate Professor

The University of British Columbia

CANADA

Sarah Hedtrich (nee Küchler)

The University of British Columbia

CANADA

Don D. Sin

The University of British Columbia

CANADA

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