Timothy Holsgrove

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Lecturer - Biomechanics & Bioengineering

University of Exeter

United Kingdom

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About

Timothy Holsgrove is a Lecturer in Biomechanics and Bioengineering at the University of Exeter, UK. His research primarily focuses on the mechanobiology of the intervertebral disc, exploring its mechanical properties and responses under various loading conditions. Recent publications highlight his work on finite element models, in-vitro models of degeneration, and the effects of external forces on cognitive and motor functions.

Recent Grants

Grant: Close

Image-driven subject-specific spine models

Open Date: 2021-09-30

Close Date: 2024-09-29

Grant: Close

A mechanobiochemical investigation into intervertebral disc health - A multidisciplinary approach using in-vivo, in-vitro, and in-silico methods

Open Date: 2021-09-30

Close Date: 2025-03-30

Grant: Close

The development and implementation of a six-axis bioreactor for regenerative therapies of the intervertebral disc

Open Date: 2020-01-01

Close Date: 2022-12-31

Articles (16)

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2025

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2021

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2020

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2020

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2020

Collaborators (6)

Bert Bond

Senior Lecturer

University of Exeter

UNITED KINGDOM

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Francesca Palombo

Professor of Biomedical Spectroscopy

University of Exeter

UNITED KINGDOM

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Justin J. Cooper-White

University of Queensland

AUSTRALIA

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Nicolas Newell

UNITED KINGDOM

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David Harris

University of Exeter

UNITED KINGDOM

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Grace D. O’Connell

UNITED STATES

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Timothy Holsgrove

Research Interests

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Recent Grants

Articles (16)

Optimisation of Intervertebral Disc Mechanical Properties and the Impact of Vertebral Alignment in Subject‐Specific Finite Element Models

Six-Axis, Physiological Activity Profiles Create a More Challenging Cellular Environment in the Intervertebral Disc Compared to Single-Axis Loading

Do we know more about the mechanobiology of the intervertebral disc in space than on Earth?

The after-effects of occupational whole-body vibration on human cognitive, visual, and motor function: A systematic review

A novel in-vitro model of intervertebral disc degeneration using hyperphysiological loading

Replicating spine loading during functional and daily activities: An in vivo, in silico, in vitro research pipeline

The physiological, in-vitro simulation of daily activities in the intervertebral disc using a load Informed kinematic evaluation (LIKE) protocol

Stirred Not Shaken: A Longitudinal Pilot Study of Head Kinematics and Cognitive Changes in Horseracing

PUBLIC AND PATIENT ENGAGEMENT IN RESEARCH TO DEVELOP TECHNOLOGIES FOR PREDICTING SPINE LOADS IN VIVO

The role of biomechanical factors in models of intervertebral disc degeneration across multiple length scales

BORS/BJR TRAVELLING FELLOWSHIP: IMAGE-DRIVEN SUBJECT-SPECIFIC SPINE MODELS: DEVELOPING A NOVEL TOOL TO MEASURE IN VIVO LOADING

In-vitro models of disc degeneration – A review of methods and clinical relevance

Thunder road - whole-body vibration during road cycling, and the effect of different seatpost designs to minimise it

Viscoelastic properties of biopolymer hydrogels determined by Brillouin spectroscopy: A probe of tissue micromechanics

Influence of testing environment and loading rate on intervertebral disc compressive mechanics: An assessment of repeatability at three different laboratories

Pain after whole-body vibration exposure is frequency dependent and independent of the resonant frequency: Lessons from an in vivo rat model

Collaborators (6)

Bert Bond

Francesca Palombo

Justin J. Cooper-White

Nicolas Newell

David Harris

Grace D. O’Connell

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