Tohru Hosoyama

Associate Professor

National Center for Geriatrics and Gerontology

Japan

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About

Tohru Hosoyama is an Associate Professor at the National Center for Geriatrics and Gerontology in Japan. His research areas focus on sarcopenia, adipogenesis, and frailty in aging populations, with recent articles examining the genetic factors and biomarkers associated with these conditions. He also investigates the impacts of vitamin D signaling and exercise on muscle health and age-related health outcomes.

Articles (13)

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2025

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2025

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2024

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2024

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2024

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2024

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2024

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2024

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2023

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2022

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2021

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2020

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2020

Collaborators (2)

Takashi Matsuwaki

The Univeristy of Tokyo

JAPAN

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Shinya Ishizuka

Lecturer

Nagoya Daigaku

JAPAN

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Tohru Hosoyama

Research Interests

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Articles (13)

Identification of a risk allele at SLC41A3 and a protective allele HLA-DPB1*02:01 associated with sarcopenia in Japanese

PDZRN3 regulates adipogenesis of mesenchymal progenitors in muscle

Lack of vitamin D signalling in mesenchymal progenitors causes fatty infiltration in muscle

Postnatal Pdzrn3 deficiency causes acute muscle atrophy without alterations in endplate morphology

Association of biomarkers and Barthel Index with occurrence of age‐related adverse health outcomes in individuals with diabetes

Roles of pigment epithelium-derived factor in exercise-induced suppression of senescence and its impact on lung pathology in mice

Association between Circulating Levels of CXCL9 and CXCL10 and Physical Frailty in Older Adults

Identification of Potential Blood-Based Biomarkers for Frailty by Using an Integrative Approach

RNA-Sequencing Analysis Identification of Potential Biomarkers for Diagnosis of Sarcopenia.

Influence of vitamin D on sarcopenia pathophysiology: A longitudinal study in humans and basic research in knockout mice

Suppression of MyoD induces spontaneous adipogenesis in skeletal muscle progenitor cell culture.

Vitamin D Inhibits Myogenic Cell Fusion and Expression of Fusogenic Genes.

Possible application of muscle specific conditional mouse-derived induced pluripotent stem cells for muscle research.

Collaborators (2)

Takashi Matsuwaki

Shinya Ishizuka

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