TOMIZUKA KAZUMA

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Tokyo University of Pharmacy and Life Sciences

Japan

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Recent Grants

Grant: Open

免疫系ヒト化動物を活用した抗感染症ヒト抗体創成基盤の確立

Open Date: 2021-04-01

Close Date: 2027-03-31

Articles (10)

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2025

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2025

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2024

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2024

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2024

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2023

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2023

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2023

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2022

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2022

Collaborators (4)

Hiroyuki Satofuka

Tohoku University

JAPAN

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Yutaro Yada

Kyushu University

JAPAN

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Corwin Nycholat

Chief Scientific Officer

UNITED STATES

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Kyotaro Yamazaki

特任助教/Research Assistant Professor

自然科学研究機構　生命創成探究センター/Exploratory Research Center on Life and Living Systems

JAPAN

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TOMIZUKA KAZUMA

Research Interests

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Recent Grants

Articles (10)

Generation of Monosomy 21q Human iPS Cells by CRISPR/Cas9-Mediated Interstitial Megabase Deletion

Human artificial chromosome carrying R-spondin1 and IL-22 expression cassettes in rejuvenated MSCs enhances therapeutic efficacy in ulcerative colitis model mice

Microcell-mediated chromosome transfer between non-identical human iPSCs

R-Spondin1 protects gastric stem cells and mitigates gastric GVHD in allogeneic hematopoietic stem cell transplantation

Rapid human genomic DNA cloning into mouse artificial chromosome via direct chromosome transfer from human iPSC and CRISPR/Cas9-mediated translocation

Full-length human dystrophin on human artificial chromosome compensates for mouse dystrophin deficiency in a Duchenne muscular dystrophy mouse model

Publisher Correction: Simultaneous loading of PCR-based multiple fragments on mouse artificial chromosome vectors in DT40 cell for gene delivery (Scientific Reports, (2022), 12, 1, (21790), 10.1038/s41598-022-25959-9)

Treatment of CHO cells with Taxol and reversine improves micronucleation and microcell-mediated chromosome transfer efficiency

Enhancement of Gene Knockdown on CD22-Expressing Cells by Chemically Modified Glycan Ligand-siRNA Conjugates.

Efficient human-like antibody repertoire and hybridoma production in trans-chromosomic mice carrying megabase-sized human immunoglobulin loci

Collaborators (4)

Hiroyuki Satofuka

Yutaro Yada

Corwin Nycholat

Kyotaro Yamazaki

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