Toshiaki Tsuchitani

Assistant Professor

Keio University Faculty of Pharmacy

Japan

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Toshiaki Tsuchitani is an Assistant Professor at Keio University Faculty of Pharmacy in Japan. His research focuses on pharmacology and pharmacokinetics, with recent articles exploring topics such as the IC50 variability of dolutegravir, nonlinear pharmacokinetics of telmisartan, and the impact of various juices on drug absorption. He is dedicated to bridging in vitro and clinical data to enhance drug development and understanding of therapeutic efficacy.

Articles (9)

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2025

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2024

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2024

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2023

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2022

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2022

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2022

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2021

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2021

Collaborators (3)

Hitoshi Kawazoe

Associate Professor

Keio University Faculty of Pharmacy

JAPAN

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Kunal Taskar

Global Head PBPK Modeling

GSK

UNITED KINGDOM

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Hisakazu Ohtani

JAPAN

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Toshiaki Tsuchitani

Research Interests

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Articles (9)

Bridging in vitro and clinical data: Experimental insights into the IC50 variability of dolutegravir as an organic cation transporter 2 inhibitor

Trends of in vitro pharmacological potency and in vivo pharmacokinetics parameters of modern drugs: Can the therapeutic/subtherapeutic dose be estimated from in vitro Ki and pharmacokinetic parameters?

Elucidating nonlinear pharmacokinetics of telmisartan: Integration of target‐mediated drug disposition and OATP1B3‐mediated hepatic uptake in a physiologically based model

The Effects of Jabara Juice on the Intestinal Permeation of Fexofenadine

Using an online journal club to improve Asian speakers' comfort in using English to discuss and understand research papers written in English.

Inhibitory Effects of Cranberry Juice and Its Components on Intestinal OATP1A2 and OATP2B1: Identification of Avicularin as a Novel Inhibitor

Mechanistic bottom-up estimation of passive drug absorption from the gastrointestinal tract: Comparison among primary cultured human intestinal cells, Caco-2 cells, artificial membrane, and animal scale-up

Digoxin absorption decreased independently of P-gp activity in rats with irinotecan-induced gastrointestinal damage

Relative contributions of metabolic enzymes to systemic elimination can be estimated from clinical DDI studies: Validation using an in silico approach

Collaborators (3)

Hitoshi Kawazoe

Kunal Taskar

Hisakazu Ohtani

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