Tsui-Fen Chou

Research Professor

California Institute of Technology

United States

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Tsui-Fen Chou is a Research Professor at the California Institute of Technology, USA. Her research primarily focuses on mitochondria, proteomics, and chromatin state, as demonstrated by her recent publications exploring mitophagy, protein production, and innovative nanoformulations in cancer therapy. She is engaged in advancing understanding of protein dynamics and cellular stress responses.

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2025

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2021

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2020

Collaborators (5)

Chao Qin

Research Assistant Professor

University of Southern California

UNITED STATES

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David Chan

Professor

California Institute of Technology

UNITED STATES

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Chieh-Hsiang Tan

California Institute of Technology

UNITED STATES

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Samuel Kharpatin

University of California, Los Angeles

UNITED STATES

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Robert Damoiseaux

Professor & Director

UCLA Health

UNITED STATES

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Tsui-Fen Chou

Research Interests

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About

Articles (20)

Putative PINK1/Parkin Activators Lower the Threshold for Mitophagy by Sensitizing Cells to Mitochondrial Stress

PLAA/UFD-3 regulates P-bodies through its intrinsic disordered domain

Optimizing Protein Production in the One-Pot PURE System: Insights into Reaction Composition and Expression Efficiency

In-Depth Comparison of Reagent-Based Digestion Methods and Two Commercially Available Kits for Bottom-Up Proteomics

Single-tissue proteomics in Caenorhabditis elegans reveals proteins resident in intestinal lysosome-related organelles

N-Myristoytransferase Inhibition Causes Mitochondrial Iron Overload and Parthanatos in TIM17A-Dependent Aggressive Lung Carcinoma

Increasing Proteome Coverage Through a Reduction in Analyte Complexity in Single-Cell Equivalent Samples

An innovative nanoformulation utilizing tumor microenvironment-responsive PEG-polyglutamic coating and dynamic charge adjustment for specific targeting of ER stress inducer, microRNA, and immunoadjuvant in pancreatic cancer: In vitro investigations

Cryptic phosphoribosylase activity of NAMPT restricts the virion incorporation of viral proteins

Impact of Germline Depletion of Bonus on Chromatin State in Drosophila Ovaries

P97/VCP ATPase inhibitors can rescue p97 mutation-linked motor neuron degeneration

Sulforaphane is Synergistic with CB‐5083 and Inhibits Colony Formation of CB‐5083‐Resistant HCT116 Cells

NMS-873 Leads to Dysfunctional Glycometabolism in A p97-Independent Manner in HCT116 Colon Cancer Cells

Temporal proteomics reveal specific cell cycle oncoprotein downregulation by p97/VCP inhibition

The p97 Inhibitor UPCDC-30245 Blocks Endo-Lysosomal Degradation

Impacts of p97 on Proteome Changes in Human Cells during Coronaviral Replication

Conserved L464 in p97 D1–D2 linker is critical for p97 cofactor regulated ATPase activity

Evaluation of artificial signal peptides for secretion of two lysosomal enzymes in CHO cells

A covalent p97/VCP ATPase inhibitor can overcome resistance to CB-5083 and NMS-873 in colorectal cancer cells

Allosteric p97 Inhibitors Can Overcome Resistance to ATP‐Competitive p97 Inhibitors for Potential Anticancer Therapy

Collaborators (5)

Chao Qin

David Chan

Chieh-Hsiang Tan

Samuel Kharpatin

Robert Damoiseaux

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