Tsuyoshi Nishiguchi

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Assistant Professor

Tohoku University Hospital

Japan

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About

Tsuyoshi Nishiguchi is an Assistant Professor at Tottori University Hospital in Japan. His research interests encompass the study of delirium, particularly in relation to type 2 diabetes, postoperative conditions, and inflammation. Recent articles include investigations into the effects of Metformin on delirium and the role of bispectral electroencephalography in assessing and quantifying delirium-like states. He is also exploring the effects of beta-hydroxybutyrate on anxiety and depression in rodent models, contributing to a deeper understanding of neuroinflammation and mental health.

Recent Grants

Grant: Close

Potential of β-hydroxybutyrate as a new pathological diagnostic marker for depression.

Open Date: 2022-04-01

Close Date: 2024-03-01

Articles (9)

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2025

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2024

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2024

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2024

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2023

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2022

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2021

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2020

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2020

Collaborators (3)

Masaaki Iwata

Associate Professor

Toho University Faculty of Medicine

JAPAN

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Tomoteru Seki

University of Tokyo Hospital

JAPAN

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Gen Shinozaki

Associate Professor

Stanford University School of Medicine

UNITED STATES

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Tsuyoshi Nishiguchi

Research Interests

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About

Recent Grants

Articles (9)

Associations of Metformin Use History With Delirium and Mortality in Patients With Type 2 Diabetes Mellitus: A Retrospective Cohort Study

Lipopolysaccharide-Induced Delirium-Like Behavior and Microglial Activation in Mice Correlate With Bispectral Electroencephalography

Discovery of novel protective agents for infection-related delirium through bispectral electroencephalography

The Bispectral Electroencephalography Method Quantifies Postoperative Delirium-Like States in Young and Aged Male Mice After Head-Mount Implantation Surgery

Bispectral EEG (BSEEG) algorithm captures high mortality risk among 1077 patients: its relationship to delirium motor subtype

Genome-wide DNA methylation analysis of post-operative delirium with brain, blood, saliva, and buccal samples from neurosurgery patients

Stress increases blood beta‐hydroxybutyrate levels and prefrontal cortex NLRP3 activity jointly in a rodent model

Prefrontal cortex infusion of beta‐hydroxybutyrate, an endogenous NLRP3 inflammasome inhibitor, produces antidepressant‐like effects in a rodent model of depression

Beta-hydroxybutyrate, an endogenous NLRP3 inflammasome inhibitor, attenuates anxiety-related behavior in a rodent post-traumatic stress disorder model

Collaborators (3)

Masaaki Iwata

Tomoteru Seki

Gen Shinozaki

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