Umberto Piarulli

Professore Ordinario

Università degli Studi di Roma La Sapienza

Italy

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Umberto Piarulli is a Professore Ordinario at Università degli Studi dell'Insubria, Italy. His research focuses on areas such as drug conjugates targeting MDM2 and tumor-specific linkers, chiral iron complexes in organic transformations, and the development of cell-penetrating peptides for anti-cancer therapies. His recent publications explore innovative approaches in synthetic organic chemistry and biological evaluation methods.

Articles (10)

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2025

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2024

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2023

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2022

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2022

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2022

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2021

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2020

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2020

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2020

Collaborators (4)

Luca Pignataro

Associate Professor

Università degli Studi di Torino

ITALY

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Valentina Colombo

Prof. Dr.

Università degli Studi di Torino

ITALY

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SILVIA GAZZOLA

Assistent Professor in Organic Chemistry

Università degli Studi di Modena e Reggio Emilia Dipartimento di Scienze della Vita

ITALY

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Laura Belvisi

Professor

University of Milan

ITALY

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Umberto Piarulli

Research Interests

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Articles (10)

Comparative Enzymatic and Stability Assays Reveal GPLG as an Effective Cathepsin B Cleavable Linker for Tumor-Targeting Drug Conjugates

Design, Synthesis and Preliminary In‐Vitro Activity of 6‐Hydroxyalkyl β‐Carboline Derivatives for the Development of Drug Conjugates Targeting MDM2

Design, Synthesis and Catalytic Activity of (Cyclopentadienone)iron Complexes Containing a Stereogenic Plane and a Stereogenic Axis

A Long Journey through Organic Chemistry – Celebrating Cesare Gennari's 70th Birthday

A combined fragment-based virtual screening and STD-NMR approach for the identification of E-cadherin ligands

Chiral Iron Complexes in Asymmetric Organic Transformations

Synthesis and Biological Evaluation of an isoDGR‐Paclitaxel Conjugate Containing a Cell‐Penetrating Peptide to Promote Cellular Uptake

Cyclic RGD and <i>iso</i>DGR Integrin Ligands Containing <i>cis</i>-2-amino-1-cyclopentanecarboxylic (<i>cis</i>-β-ACPC) Scaffolds

Cell-penetrating peptides containing 2,5-diketopiperazine (DKP) scaffolds as shuttles for anti-cancer drugs: conformational studies and biological activity

Cell-penetrating peptides containing 2,5-diketopiperazine (DKP) scaffolds as shuttles for anti-cancer drugs: Conformational studies and biological activity

Collaborators (4)

Luca Pignataro

Valentina Colombo

SILVIA GAZZOLA

Laura Belvisi

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