Valeria Tiranti

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Associate Professor

Fondazione IRCCS Istituto Neurologico Carlo Besta

Italy

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Recent Grants

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Implementation of human neuronal cultures and mouse models of Pantothenate kinase 2 deficiency to investigate pathogenic mechanisms of iron-related neurodegeneration and evaluate Coenzyme A therapeutic efficacy

Open Date: 2017-02-01

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Articles (10)

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2023

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2023

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2023

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2023

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2022

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2022

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2021

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2021

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2020

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2020

Collaborators (7)

Sophie Ayciriex, PhD

Associate Professor

Université Claude Bernard Lyon 1 Faculté des Sciences et Technologies

FRANCE

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Camille Péron

Fondazione IRCCS Istituto Neurologico Carlo Besta

ITALY

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Andrea Cavaliere

Fondazione IRCCS Istituto Neurologico Carlo Besta

ITALY

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Prigione Alessandro

Heinrich Heine University Düsseldorf

GERMANY

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Sonia Levi

Full Professor

Vita-Salute San Raffaele University

ITALY

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Giulia Massaro

Lecturer and Principal Investigator

University College London

UNITED KINGDOM

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Emanuela Bottani

Assistant Professor, Tenure Track

University of Verona

ITALY

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Valeria Tiranti

Research Interests

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Recent Grants

Articles (10)

Modeling mitochondrial DNA diseases: from base editing to pluripotent stem‐cell‐derived organoids

PPAR Gamma Agonist Leriglitazone Recovers Alterations Due to Pank2-Deficiency in hiPS-Derived Astrocytes

Inherited Disorders of Coenzyme A Biosynthesis: Models, Mechanisms, and Treatments

Mitochondrial Transplantation in Mitochondrial Medicine: Current Challenges and Future Perspectives

Gene Therapy for Mitochondrial Diseases: Current Status and Future Perspective

Massive iron accumulation in PKAN-derived neurons and astrocytes: light on the human pathological phenotype

TFG binds LC3C to regulate ULK1 localization and autophagosome formation.

Generation of two human iPSC lines, FINCBi002-A and FINCBi003-A, carrying heteroplasmic macrodeletion of mitochondrial DNA causing Pearson's syndrome.

Neuronal Ablation of CoA Synthase Causes Motor Deficits, Iron Dyshomeostasis, and Mitochondrial Dysfunctions in a CoPAN Mouse Model

Therapeutic Approaches to Treat Mitochondrial Diseases: “One-Size-Fits-All” and “Precision Medicine” Strategies

Collaborators (7)

Sophie Ayciriex, PhD

Camille Péron

Andrea Cavaliere

Prigione Alessandro

Sonia Levi

Giulia Massaro

Emanuela Bottani

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