Vishal Patel

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Honorary Reader in Hepatology

King’s College London

United Kingdom

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About

Vishal Patel serves as an Honorary Reader in Hepatology at King's College London. His research primarily focuses on the interactions between the microbiome and liver diseases, as evidenced by his recent articles on fecal microbiota transplantation and its effects on hepatic encephalopathy, as well as the role of microRNA in predicting outcomes for cirrhotic patients. His work also explores lipidomics and bile acid metabolism in alcohol-related hepatitis. Based in the UK, he contributes significantly to advancing the understanding of hepatology.

Recent Grants

Grant: Close

Applying circulating cell-free DNA methylation technologies to produce novel prognostic markers in chronic liver failure syndromes

Open Date: 2021-06-01

Close Date: 2022-06-01

Grant: Close

A PROspective double-blind placebo-controlled multicentre trial of faecal MIcrobiota tranSplantation to improve outcomEs in patients with cirrhosis - PROMISE trial.

Open Date: 2021-05-01

Close Date: 2026-04-30

Grant: Close

Faecal Microbiota transplantation to prevent complications, progression and mortality of cirrhosis

Open Date: 2021-01-01

Close Date: 2026-01-01

Grant: Close

The role of cell free DNA as a driver of coagulation dysfunction and critical illness in chronic liver disease

Open Date: 2020-02-01

Close Date: 2021-05-01

Grant: Close

Beta-blockers or placebo for primary prophylaxis of oesophageal varices (BOPPP study)

Open Date: 2019-01-01

Close Date: 2024-09-30

Articles (21)

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2021

Collaborators (19)

Brian Hogan

Honorary Associate Professor

University College London

UNITED KINGDOM

Vishal Patel

Research Interests

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About

Recent Grants

Articles (21)

FMT for hepatic encephalopathy? The THEMATIC trial aims to make it a ‘no brainer’

Lipidomics-based plasma signature of alcohol-related hepatitis linked to short-term mortality

Oral-gut microbiome interactions in advanced cirrhosis: characterisation of pathogenic enterotypes and salivatypes, virulence factors and antimicrobial resistance

Beta-blockers or Placebo for Primary Prophylaxis (BOPPP) of oesophageal varices

Von Willebrand factor as a predictor of mortality in acute‐on‐chronic liver failure: Do not throw out the baby with the bathwater

Oral-gut microbiome interactions in advanced cirrhosis

microRNA associated with hepatocyte injury and systemic inflammation may predict adverse outcomes in cirrhotic patients

microRNA associated with hepatocyte injury and systemic inflammation may predict adverse outcomes in cirrhotic patients

Alcohol-related hepatitis is associated with a distinctive pattern of disordered bile acid metabolism and reduced bile acid transporter expression

Beta-blockers or Placebo for Primary Prophylaxis (BOPPP) of oesophageal varices: study protocol for a randomised controlled trial

Faecal microbiota transplantation in patients with cirrhosis, reduces antimicrobial resistance and enteric pathogen carriage, and enhances intestinal barrier function, associated with bacteriophage remodelling

Von Willebrand factor is an independent predictor of short‐term mortality in acutely ill patients with cirrhosis

Carvedilol in patients with compensated cirrhosis: The ongoing benefits of definitive randomised trials over meta-analysis in patients with small varices

Lysophosphatidylcholines modulate immunoregulatory checkpoints in peripheral monocytes and are associated with mortality in people with acute liver failure

General practitioner perspectives on factors that influence implementation of secondary care-initiated treatment in primary care: Exploring implementation beyond the context of a clinical trial

Using a theory-informed approach to explore patient and staff perspectives on factors that influence clinical trial recruitment for patients with cirrhosis and small oesophageal varices

Fibrin clot quality in acutely ill cirrhosis patients: Relation with outcome and improvement with coagulation factor concentrates

Aberrant hepatic trafficking of gut-derived T cells is not specific to primary sclerosing cholangitis

Rifaximin-α reduces gut-derived inflammation and mucin degradation in cirrhosis and encephalopathy: RIFSYS randomised controlled trial.

Prevalence of Bleeding and Thrombosis in Critically Ill Patients with Chronic Liver Disease

Dysregulation of the Lysophosphatidylcholine/Autotaxin/Lysophosphatidic Acid Axis in Acute-on-Chronic Liver Failure Is Associated With Mortality and Systemic Inflammation by Lysophosphatidic Acid–Dependent Monocyte Activation

Collaborators (19)

Brian Hogan

Lindsey Ann Edwards

Arjuna Singanayagam

Vanessa Lawrence

Elaine Holmes

Giorgina Mieli-Vergani

Ton Lisman

Clair Le Boutillier

Mark J. W. McPhail

Naaventhan Palaniyappan

Annabel Blasi Ibanez

Shilpa Chokshi

Bu'Hussain Hayee

Hassan Jafari

Ian D. Wilson

Debbie Shawcross

Ben Carter

Saeed Shoaie

Haroon Ahmed

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