Wei-Chung Lee

Associate Professor

Harvard Medical School

United States

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Wei-Chung Lee is an Associate Professor at Harvard Medical School in the United States. His research primarily focuses on neuronal tissue imaging, connectomics, and the structural characteristics of the blood-brain barrier. Notable recent publications include studies on Drosophila neuronal connections, the effects of intracellular structures on neuron differentiation, and synaptic architectures involved in motor control and decision-making.

Articles (20)

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2025

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2021

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2020

Collaborators (9)

Saikat Mukhopadhyay

UNITED STATES

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Andrew Dacks

Associate Professor

Case Western Reserve University

UNITED STATES

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Ilaria Ricchi

EPFL (École Polytechnique Fédérale de Lausanne)

SWITZERLAND

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Evan Macosko

Assistant Professor

Massachusetts General Hospital

UNITED STATES

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Stefano Panzeri

Professor

University Medical Center Hamburg-Eppendorf

GERMANY

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Rachel Wilson

Martin Family Professor of Basic Research in the Field of Neurobiology

Harvard Medical School

UNITED STATES

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Uri Manor

Assistant Research Professor

Salk Institute for Biological Studies

UNITED STATES

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Srinivas Turaga

Howard Hughes Medical Institute Janelia Farm Research Campus

UNITED STATES

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Sweta Agrawal

Assistant Professor

Virginia Tech

UNITED STATES

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Wei-Chung Lee

Research Interests

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About

Articles (20)

Scaling up X-ray holographic nanotomography for neuronal tissue imaging

Comparative connectomics of Drosophila descending and ascending neurons.

Permanent deconstruction of intracellular primary cilia in differentiating granule cell neurons

Synaptic wiring motifs in posterior parietal cortex support decision-making

Characteristics of blood-brain barrier heterogeneity between brain regions revealed by profiling vascular and perivascular cells.

Connectomic reconstruction of a female Drosophila ventral nerve cord.

Synaptic architecture of leg and wing premotor control networks in Drosophila.

Ultrastructural differences impact cilia shape and external exposure across cell classes in the visual cortex.

Specialized connectivity of molecular layer interneuron subtypes leads to disinhibition and synchronous inhibition of cerebellar Purkinje cells.

Organization of an ascending circuit that conveys flight motor state in Drosophila.

Local shape descriptors for neuron segmentation

The projection-specific signals that establish functionally segregated dopaminergic synapses.

Biomechanical origins of proprioceptor feature selectivity and topographic maps in the Drosophila leg.

Candelabrum cells are ubiquitous cerebellar cortex interneurons with specialized circuit properties

Structured cerebellar connectivity supports resilient pattern separation.

Astrocyte-neuron crosstalk through Hedgehog signaling mediates cortical synapse development.

Automatic detection of synaptic partners in a whole-brain Drosophila electron microscopy data set

Functional architecture of neural circuits for leg proprioception in Drosophila.

Reconstruction of motor control circuits in adult Drosophila using automated transmission electron microscopy.

A petascale automated imaging pipeline for mapping neuronal circuits with high-throughput transmission electron microscopy.

Collaborators (9)

Saikat Mukhopadhyay

Andrew Dacks

Ilaria Ricchi

Evan Macosko

Stefano Panzeri

Rachel Wilson

Uri Manor

Srinivas Turaga

Sweta Agrawal

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