Weihua Guan

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Associate Professor

Pennsylvania State University

United States

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About

Weihua Guan is an Associate Professor at Pennsylvania State University, USA. His research focuses on innovative point-of-care testing methods, particularly for viral infections and diseases such as HIV, HCV, COVID-19, and Alzheimer’s. His recent publications highlight advancements in multiplexed diagnostic techniques and nanotechnology applications in biomedical testing.

Recent Grants

Grant: Close

CAREER: Amplification-Coupled Solid-State Nanopore Digital Counting based a Versatile Platform for Point-of-Care Nucleic Acid Testing

Open Date: 2021-06-01

Close Date: 2026-05-31

Grant: Close

Home Fingerprick Blood-Based HIV Self-Test For Quantitative Monitoring Of Viral Rebound

Open Date: 2020-09-01

Close Date: 2023-08-31

Grant: Close

Quantitative microfluidic NAT-on-USB: towards routine HIV viral load testing

Open Date: 2019-08-01

Close Date: 2022-07-31

Grant: Close

Ultracompact sample-to-answer nucleic acid test on USB stick

Open Date: 2019-08-01

Close Date: 2022-07-31

Grant: Close

Nanofluidic Charge Coupled Devices for Molecular Separation and Sensing

Open Date: 2017-08-01

Close Date: 2020-07-31

Articles (20)

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2022

Collaborators (2)

Yusheng Zhu

PROFESSOR, MEDICAL DIRECTOR

Penn State College of Medicine

UNITED STATES

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Xiang Li

Indiana State University

UNITED STATES

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Weihua Guan

Research Interests

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About

Recent Grants

Articles (20)

Point-of-need one-pot multiplexed RT-LAMP test for detecting three common respiratory viruses in saliva

Rapid simultaneous self-testing of HIV and HCV viral loads with integrated RNA extraction and multiplex RT-PCR in under 1 hour

Solid-State Nanopore Sizing for cfDNA Sample Quality Control in Point-of-Need Sequencing

Multiplexed Salivary miRNA Quantification for Predicting Severe COVID-19 Symptoms in Children Using Ligation-RPA Amplification Assay

Extracellular vesicle-based point-of-care testing for diagnosis and monitoring of Alzheimer’s disease

Addressing Buffer, Size, and Clogging Challenges in LAMP-Coupled Solid-State Nanopores for Point-of-Care Testing

Compact multiplex PCR device for HIV-1 and HIV-2 viral load determination from finger-prick whole blood in resource-limited settings

Opportunities and challenges in implementing CRISPR-based point-of-care testing for Monkeypox detection

CRISPR-based strategies for sample-to-answer monkeypox detection: current status and emerging opportunities

Hydrogel interfaced glass nanopore for high-resolution sizing of short DNA fragments

STAMP-Based Digital CRISPR-Cas13a for Amplification-Free Quantification of HIV-1 Plasma Viral Loads

Morphology around Nanopores Fabricated by Laser-Assisted Dielectric Breakdown and Its Impact on Ion and DNA Transport and Sensing

Handheld Purification-Free Nucleic Acid Testing Device for Point-of-Need Detection of Malaria from Whole Blood

Digital CRISPR systems for the next generation of nucleic acid quantification

Programmable magnetic robot (ProMagBot) for automated nucleic acid extraction at the point of need

Modeling pyramidal silicon nanopores with effective ion transport

SLIDE: Saliva-Based SARS-CoV-2 Self-Testing with RT-LAMP in a Mobile Device

Fingerpick Blood-Based Nucleic Acid Testing on A USB Interfaced Device towards HIV self-testing

Figure of Merit for CRISPR-Based Nucleic Acid-Sensing Systems: Improvement Strategies and Performance Comparison

Rolling Circle Amplification-Coupled Glass Nanopore Counting of Mild Traumatic Brain Injury-Related Salivary miRNAs

Collaborators (2)

Yusheng Zhu

Xiang Li

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