Wenhao Chen

United States

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Articles (10)

Year:

2025

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2025

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2024

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2024

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2023

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2023

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2022

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2020

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2020

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2020

Collaborators (2)

Nancy Gonzalez

Houston Methodist Research Institute

UNITED STATES

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Zheng Yin

Assistant professor

Houston Methodist Research Institute

UNITED STATES

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Wenhao Chen

Research Interests

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Articles (10)

Beyond T-cell subsets: stemness and adaptation redefining immunity and immunotherapy

Transient Anti‐TCRβ mAb Treatment Induces CD4+T Cell Exhaustion and Prolongs Survival in a Mouse Model of Systemic Lupus Erythematosus

CD4+ T cell immunity is dependent on an intrinsic stem-like program

Aerobic glycolysis enables the effector differentiation potential of stem-like CD4+ T cells to combat cancer

The transcription factor IRF4 determines the anti-tumor immunity of CD8<sup>+</sup> T cells.

Continuous Expression of Interferon Regulatory Factor 4 Sustains CD8 + T Cell Immunity against Tumor

Genetically targeting the BATF family transcription factors BATF and BATF3 in the mouse abrogates effector T cell activities and enables long-term heart allograft survival

Interferon regulatory factor 4 deficiency in CD8+ T cells abrogates terminal effector differentiation and promotes transplant acceptance

Epigenetically modifying the Foxp3 locus for generation of stable antigen-specific Tregs as cellular therapeutics

T cell exhaustion is associated with antigen abundance and promotes transplant acceptance

Collaborators (2)

Nancy Gonzalez

Zheng Yin

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