William Klein

Professor

Northwestern University

United States

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William Klein is a Professor at Northwestern University in the United States. His research primarily focuses on neurodegenerative diseases, particularly Alzheimer's disease, with recent publications exploring amyloid beta oligomers, their mechanisms, and therapeutic interventions. He has contributed significantly to understanding the role of amyloid beta in both neurodevelopment and disease pathology.

Articles (7)

Year:

2025

Year:

2023

Year:

2023

Year:

2022

Year:

2022

Year:

2022

Year:

2021

Collaborators (5)

Helena Janickova

CANADA

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Marco Antonio Maximo Prado

Professor

University of Western Ontario

CANADA

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Steven M. Patrie

Northwestern University

UNITED STATES

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Hongxin Dong

Professor

Northwestern University

UNITED STATES

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Maria Clara Selles

New York University

UNITED STATES

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William Klein

Research Interests

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Articles (7)

Inhibition of amyloid beta oligomer accumulation by NU-9: A unifying mechanism for the treatment of neurodegenerative diseases.

Amyloid β Proteoforms Elucidated by Quantitative LC/MS in the 5xFAD Mouse Model of Alzheimer’s Disease

Pharmacological inhibition of plasminogen activator inhibitor-1 prevents memory deficits and reduces neuropathology in APP/PS1 mice.

AAV-mediated neuronal expression of an scFv antibody selective for Aβ oligomers protects synapses and rescues memory in Alzheimer models

A time for optimism in the dementia field.

An Essential Role for Alzheimer’s-Linked Amyloid Beta Oligomers in Neurodevelopment: Transient Expression of Multiple Proteoforms during Retina Histogenesis

Induction of inverted morphology in brain organoids by vertical-mixing bioreactors

Collaborators (5)

Helena Janickova

Marco Antonio Maximo Prado

Steven M. Patrie

Hongxin Dong

Maria Clara Selles

Make your next move.

William Klein

Research Interests

Explore related searches

Contact this professor

About

Articles (7)

Inhibition of amyloid beta oligomer accumulation by NU-9: A unifying mechanism for the treatment of neurodegenerative diseases.

Amyloid β Proteoforms Elucidated by Quantitative LC/MS in the 5xFAD Mouse Model of Alzheimer’s Disease

Pharmacological inhibition of plasminogen activator inhibitor-1 prevents memory deficits and reduces neuropathology in APP/PS1 mice.

AAV-mediated neuronal expression of an scFv antibody selective for Aβ oligomers protects synapses and rescues memory in Alzheimer models

A time for optimism in the dementia field.

An Essential Role for Alzheimer&rsquo;s-Linked Amyloid Beta Oligomers in Neurodevelopment: Transient Expression of Multiple Proteoforms during Retina Histogenesis

Induction of inverted morphology in brain organoids by vertical-mixing bioreactors

Collaborators (5)

Helena Janickova

Marco Antonio Maximo Prado

Steven M. Patrie

Hongxin Dong

Maria Clara Selles

Make your next move.

An Essential Role for Alzheimer’s-Linked Amyloid Beta Oligomers in Neurodevelopment: Transient Expression of Multiple Proteoforms during Retina Histogenesis