William Wuest

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GRA Distinguished Investigator and Professor

Emory University

United States

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Recent Grants

Grant: Close

Development of Natural-Product Inspired Ubiquinone Mimics as Next Generation Agrochemicals

Open Date: 2020-06-01

Close Date: 2023-05-01

Grant: Close

Development of Natural Product-Inspired Ubiquinone Mimics as Next Generation Agrochemicals

Open Date: 2020-06-01

Close Date: 2023-05-31

Grant: Close

CAREER: The Bioorganic Investigation of Species-Specific Biofilm Modulators

Open Date: 2017-06-01

Close Date: 2020-04-30

Grant: Close

Tool Compounds to Probe Multispecies Biofilms in the Human Oral Microbiome

Open Date: 2016-08-01

Close Date: 2021-07-31

Grant: Close

Natural Product-Inspired Approaches Toward the Development of Antivirulence and Species-Specific Inhibitors

Open Date: 2016-06-30

Close Date: 2021-05-31

Articles (18)

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2023

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2023

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2022

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2022

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2022

Collaborators (4)

Graeme Conn

Professor

Emory University School of Medicine

UNITED STATES

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Christian Sanchez

Assistant Professor

Samford University

UNITED STATES

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Savannah Post

Assistant Professor

Berry College

UNITED STATES

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Hui wu

Professor/Associate Dean of Research

Oregon Health & Science University

UNITED STATES

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William Wuest

Research Interests

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Recent Grants

Articles (18)

Adaptations to cationic biocide exposure differentially influence virulence factors and pathogenicity in Pseudomonas aeruginosa

In Situ Biofilm Affinity-Based Protein Profiling Identifies the Streptococcal Hydrolase GbpB as the Target of a Carolacton-Inspired Chemical Probe

Exploring the Correlation of Dynamic Surface Tension with Antimicrobial Activities of Quaternary Ammonium‐Based Disinfectants

Siderophores: A Case Study in Translational Chemical Biology

Mild Photochemical Reduction of Alkenes and Heterocycles via Thiol-Mediated Formate Activation

Total Synthesis and Biological Investigation of Mindapyrroles A and B

Visible-Light/Nickel-Catalyzed Carboxylation of C(sp2) Bromides via Formate Activation

A versatile strategy for the synthesis of various lumazine peptides

Double BAC and Triple BAC: A Systematic Analysis of the Disinfectant Properties of Multicationic Derivatives of Benzalkonium Chloride (BAC)

Structure-Based Design of Promysalin Analogues to Overcome Mechanisms of Bacterial Resistance

Beyond ergosterol: Strategies for combatting antifungal resistance in Aspergillus fumigatus and Candida auris

Ribosome-targeting antibiotics and resistance via ribosomal RNA methylation

Total Synthesis of the Reported Structure of Cahuitamycin A: Insights into an Elusive Natural Product Scaffold

Investigating the Role of Metabolism for Antibiotic Combination Therapies in Pseudomonas aeruginosa

Deriving Novel Quaternary Ammonium Compound Disinfectant Scaffolds from a Natural Product: Mechanistic Insights of the Quaternization of Ianthelliformisamine C

Total Synthesis and Antibacterial Investigations of 1‐Hydroxyboivinianin A

Quaternary Phosphonium Compound Unveiled as a Potent Disinfectant against Highly Resistant Acinetobacter baumannii Clinical Isolates

Rigidity‐Activity Relationships of bisQPC Scaffolds against Pathogenic Bacteria

Collaborators (4)

Graeme Conn

Christian Sanchez

Savannah Post

Hui wu

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