Wim Dehaen

Prof

KU Leuven

Belgium

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Wim Dehaen is a Professor at KU Leuven in Belgium. His research areas encompass synthetic organic chemistry, photophysics, and the development of novel chemical probes for biomedical applications. Recent publications include studies on emissive properties of dyads, synthesis of receptor agonists, and innovative approaches to diagnose chemical exposures. He contributes significantly to the understanding of structure-activity relationships in various chemical systems.

Wim Dehaen

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Articles (30)

Complex Emissive Properties of Novel Azulene‐Dimethylaniline Dyads: Insights from Experimental and Computational Studies

Synthesis and Evaluation of Phenoxybenzylpiperidinyl Analogues as Agonists of the Chemokine Receptor CCR8

Structure–Activity Relationship Study of 3-Alkynyl-6-aryl-isothiazolo[4,3-b]pyridines as Dual Inhibitors of the Lipid Kinases PIKfyve and PIP4K2C

Imination enables efficient formation of a pillararene-inspired host with endo-cavity hydrogen-bonding capability

Real-time tracking and early diagnosis of mercury(II) exposure via a novel NIR-based fluorescent probe based on thiahemicyanine dye

Reactions of acryl thioamides with iminoiodinanes as a one-step synthesis of N-sulfonyl-2,3-dihydro-1,2-thiazoles

A potent fluorescent probe for HOCl with dual NIR emissions: Achieving the early diagnosis of polystyrene microplastics-induced liver injury involved in ferroptosis

BOPAM’s Bright and Dark Excited States: Insight from Structural, Photophysical, and Quantum Chemical Investigations

Theoretical Insights into the Impact of Pyrrole and Imidazole Substituents on the BODIPY Chromophore

Front Cover: Synthesis of Thieno[2,3‐c]pyridine Derivatives by 1,2,3‐Triazole‐Mediated Metal‐Free Denitrogenative Transformation Reaction (ChemistryOpen 5/2025)

Design of anti-fouling membranes via prebiotic chemistry-inspired aminomalononitrile (AMN) coating strategy: Aldehyde-mediated chemical immobilization of pseudo-zwitterionic compounds

Palladium-Catalyzed Arylations towards 3,6-Diaryl-1,3a,6a-triazapentalenes and Evaluation of Their Fluorescence Properties

Synthesis of a 3,7-Disubstituted Isothiazolo[4,3-b]pyridine as a Potential Inhibitor of Cyclin G-Associated Kinase

Voltammetric Sensing of Chloride Based on a Redox-Active Complex: A Terpyridine-Co(II)-Dipyrromethene Functionalized Anion Receptor Deposited on a Gold Electrode

Structure-Aided Computational Design of Triazole-Based Targeted Covalent Inhibitors of Cruzipain

Synthesis and Investigation of Biological Activity of New Betulonic Acid Derivatives Containing 1,2,3-Triazole Fragments

Pillararene-inspired arenes: Synthesis, properties and applications compared to the parent macrocycle

Near-infrared boron–dipyrrin (BODIPY) nanomaterials: Molecular design and anti-tumor therapeutics

Constructing ultra-permeable pillar[5]arene-based membrane with intramolecular water channels and precise molecular fractionation

A Highly Efficient Strategy for One-Pot and Pseudo-Six-Component Synthesis of Hexahydroquinolines

Exploration of the Divergent Outcomes for the Nenitzescu Reaction of Piperazinone Enaminoesters

Exploration of Pyrido[3,4-d]pyrimidines as Antagonists of the Human Chemokine Receptor CXCR2

BOPAM: Efficient Synthesis of a Bright Asymmetric Bis‐Boron Complex and its Dark Side

Synthesis and photophysical properties of (post-)functionalized BOAHY dyes with strong aggregation-induced emission

Three-Step Synthetic Pathway toward Fully Decorated [1,2,3]Triazolo[4,5-d]pyrimidine (8-Azapurine) Derivatives

Design and synthesis of a BOAHY-derived tracker for fluorescent labeling of mitochondria

Real-time monitoring of interfacial polymerization using fluorescent dyes

Synthesis and structure–activity relationship study of phenoxybenzylpiperazine analogues as CCR8 agonists

Tandem Cycloaddition of Azides to 3,3-Diaminoacrylonitriles (2-Cyanoacetamidines) and Cornforth-Type Rearrangement as an Approach to 5-Amino-1,2,3-triazole-4-N-substituted Imidamides

Synthesis and Modification of Morphine and Codeine, Leading to Diverse Libraries with Improved Pain Relief Properties

Collaborators (11)

Luc Van Meervelt

Susana Rocha

Iwona GRABOWSKA

Mark Van der Auweraer

Dominique Schols

Ivo F. J. Vankelecom

Max Van Hoof

Tom Van Loy

Kamila MALECKA-BATURO

Wim Thielemans

Jef Rozenski

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