Xavier Darzacq

Associate professor

University of California, Berkeley

United States

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About

Xavier Darzacq is an Associate Professor at the University of California, Berkeley, United States. His research primarily focuses on live-cell single-molecule imaging and transcription biochemistry, with recent articles exploring nuclear receptor interaction networks and mechanisms of drug interactions. Additionally, he investigates the dynamics of enhancer-promoter interactions and the behavior of hypoxia-inducible factors in cellular contexts.

Articles (15)

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2025

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2025

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2025

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2024

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2023

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2023

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2022

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2022

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2022

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2022

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2021

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2021

Collaborators (2)

Anders Hansen

Assistant Professor

Massachusetts Institute of Technology

UNITED STATES

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Claire Dugast-Darzacq

Université Paris Cité

FRANCE

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Xavier Darzacq

Research Interests

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Articles (15)

Surprising features of nuclear receptor interaction networks revealed by live-cell single-molecule imaging

Surprising features of nuclear receptor interaction networks revealed by live-cell single-molecule imaging

A high-throughput platform for single-molecule tracking identifies drug interaction and cellular mechanisms

A high-throughput platform for single-molecule tracking identifies drug interaction and cellular mechanisms

Correction: Detecting molecular interactions in live-cell single-molecule imaging with proximity-assisted photoactivation (PAPA)

RNA polymerase II depletion from the inactive X chromosome territory is not mediated by physical compartmentalization

Single-molecule tracking (SMT): a window into live-cell transcription biochemistry

Enhancer–promoter interactions and transcription are largely maintained upon acute loss of CTCF, cohesin, WAPL or YY1

Mechanisms governing target search and binding dynamics of hypoxia-inducible factors

Recovering mixtures of fast-diffusing states from short single-particle trajectories

Detecting molecular interactions in live-cell single-molecule imaging with proximity-assisted photoactivation (PAPA)

The transcription factor activity gradient (TAG) model: contemplating a contact-independent mechanism for enhancer–promoter communication

Weak multivalent biomolecular interactions: a strength versus numbers tug of war with implications for phase partitioning

Structure of the human SAGA coactivator complex

Transcription activation depends on the length of the RNA polymerase II C‐terminal domain

Collaborators (2)

Anders Hansen

Claire Dugast-Darzacq

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