Xiangyou Hu

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Assistant Professor

University of Connecticut Health Center

United States

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Recent Grants

Grant: Close

Monitoring seizure activity following BACE1 inhibition for Alzheimer's disease treatment

Open Date: 2019-06-01

Close Date: 2022-01-01

Grant: Close

Pathophysiology of Lower Urinary Tract Dysfunction in a Mouse Model of Alzheimer's Disease

Open Date: 2019-01-01

Close Date: 2022-02-01

Articles (6)

Year:

2023

Year:

2022

Year:

2022

Year:

2022

Year:

2021

Year:

2020

Collaborators (3)

Manolis Kellis

Professor

Massachusetts Institute of Technology

UNITED STATES

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Riqiang Yan

Cleveland Clinic Lerner Research Institute

UNITED STATES

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Phillip P. Smith

UNITED STATES

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Xiangyou Hu

Research Interests

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Recent Grants

Articles (6)

Postnatal neuronal Bace1 deletion impairs neuroblast and oligodendrocyte maturation

Alzheimer's disease amyloidogenesis is linked to altered lower urinary tract physiology

BACE-1 inhibition facilitates the transition from homeostatic microglia to DAM-1

Targeted BACE-1 inhibition in microglia enhances amyloid clearance and improved cognitive performance

BACE1 controls synaptic function through modulating release of synaptic vesicles

Activated CX3CL1/Smad2 signals prevent neuronal loss and Alzheimer’s tau pathology-mediated cognitive dysfunction

Collaborators (3)

Manolis Kellis

Riqiang Yan

Phillip P. Smith

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