Xiaodong Cheng

The University of Texas Health Science Center at Houston

United States

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Articles (11)

Year:

2024

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2023

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2023

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2022

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2022

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2022

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2021

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2020

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2020

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2020

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2020

Collaborators (5)

Hua Liu

Principle Investigator/Associate Professor

University of Texas Medical Branch at Galveston

UNITED STATES

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Dianna M Milewicz

The University of Texas Health Science Center at Houston

UNITED STATES

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Marina Trombetta Lima

Assistant Professor

University of Groningen

NETHERLANDS

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Mark White

University of Texas Medical Branch at Galveston

UNITED STATES

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Fan Xia

University of Texas Medical Branch at Galveston

UNITED STATES

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Xiaodong Cheng

Research Interests

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Articles (11)

Protein SUMOylation promotes cAMP-independent EPAC1 activation

Paradoxes of Cellular SUMOylation Regulation: A Role of Biomolecular Condensates?

Protein SUMOylation and phase separation: partners in stress?

Pharmacological Inhibition of Epac1 Averts Ferroptosis Cell Death by Preserving Mitochondrial Integrity

Epac1 activation by cAMP regulates cellular SUMOylation and promotes the formation of biomolecular condensates

Epac1–/– and Epac2–/– mice exhibit deficient epithelial Na+ channel regulation and impaired urinary Na+ conservation

Origin and Isoform Specific Functions of Exchange Proteins Directly Activated by cAMP: A Phylogenetic Analysis

Discovery of COVID-19 Inhibitors Targeting the SARS-CoV-2 Nsp13 Helicase

Epac1 (Exchange Protein Directly Activated by cAMP 1) Upregulates LOX-1 (Oxidized Low-Density Lipoprotein Receptor 1) to Promote Foam Cell Formation and Atherosclerosis Development

Neuronal Epac1 mediates retinal neurodegeneration in mouse models of ocular hypertension.

Epac1 inhibition ameliorates pathological angiogenesis through coordinated activation of Notch and suppression of VEGF signaling.

Collaborators (5)

Hua Liu

Dianna M Milewicz

Marina Trombetta Lima

Mark White

Fan Xia

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