Xiaoyang Zhang

Assistant Professor

University of Utah

United States

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Xiaoyang Zhang is an Assistant Professor at the University of Utah, USA. His research primarily focuses on the molecular mechanisms underlying cancer development, particularly in pancreatic ductal adenocarcinoma and squamous cell carcinoma. Recent publications highlight his work on chromatin dynamics, enhancer regulation, and the role of key genetic alterations in oncogenesis.

Articles (10)

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2025

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2025

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2024

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2023

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2022

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2022

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2021

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2021

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2020

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2020

Collaborators (4)

pengfei sui

University of California, San Diego

UNITED STATES

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Bin Zheng

Professor

Cedars-Sinai Medical Center

UNITED STATES

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Estrella Aguilera Jimenez

Huntsman Cancer Institute

UNITED STATES

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Richard Moffitt

Associate Professor

Emory University

UNITED STATES

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Xiaoyang Zhang

Research Interests

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Articles (10)

Differential Control of Growth and Identity by HNF4α Isoforms in Pancreatic Ductal Adenocarcinoma

Estrogen-induced chromatin looping changes identify a subset of functional regulatory elements

3D genomic analysis reveals novel enhancer-hijacking caused by complex structural alterations that drive oncogene overexpression

TP63 fusions drive multicomplex enhancer rewiring, lymphomagenesis, and EZH2 dependence

KMT2D deficiency drives lung squamous cell carcinoma and hypersensitivity to RTK-RAS inhibition.

STAG2 regulates interferon signaling in melanoma via enhancer loop reprogramming.

A predominant enhancer co-amplified with the SOX2 oncogene is necessary and sufficient for its expression in squamous cancer.

Reprogramming of the esophageal squamous carcinoma epigenome by SOX2 promotes ADAR1 dependence.

Chromatin Looping Shapes KLF5-Dependent Transcriptional Programs in Human Epithelial Cancers.

Illuminating the noncoding genome in cancer.

Collaborators (4)

pengfei sui

Bin Zheng

Estrella Aguilera Jimenez

Richard Moffitt

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