Xu-Dong Zhu

Professor

McMaster University

Canada

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Xu-Dong Zhu is a Professor at McMaster University in Canada. His research primarily focuses on DNA replication stress, cancer therapy, and the roles of various proteins, including Cockayne Syndrome Group B protein and telomerase in cell death and telomere stability. Notable recent publications include studies on the regulation of DNA replication and repair mechanisms in BRCA2-deficient cells.

Articles (8)

Year:

2024

Year:

2023

Year:

2022

Year:

2022

Year:

2022

Year:

2021

Year:

2021

Year:

2020

Collaborators (3)

Jean Yves Masson

Full Professor

Université Laval Faculté de médecine

CANADA

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Sabine Mai

CANADA

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Sara N. Andres

CANADA

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Xu-Dong Zhu

Research Interests

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Articles (8)

CSB and SMARCAL1 compete for RPA32 at stalled forks and differentially control the fate of stalled forks in BRCA2-deficient cells

CSB Regulates Pathway Choice in Response to DNA Replication Stress Induced by Camptothecin

Consecutive Inhibition of Telomerase and Alternative Lengthening Pathway Promotes Hodgkin’s Lymphoma Cell Death

Role of Cockayne Syndrome Group B Protein in Replication Stress: Implications for Cancer Therapy.

Cockayne syndrome group B protein uses its DNA translocase activity to promote mitotic DNA synthesis.

Cockayne syndrome group B protein regulates fork restart, fork progression and MRE11-dependent fork degradation in BRCA1/2-deficient cells

The Winged Helix Domain of CSB Regulates RNAPII Occupancy at Promoter Proximal Pause Sites

CSB cooperates with SMARCAL1 to maintain telomere stability in ALT cells

Collaborators (3)

Jean Yves Masson

Sabine Mai

Sara N. Andres

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