Yan Han

Assistant Professor

University of Texas Southwestern Medical Center

United States

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Yan Han is an Assistant Professor at The University of Texas Southwestern Medical Center in the United States. His research focuses on structural biology, cellular metabolism, and protein interactions, as evidenced by his recent publications exploring therapeutic targets in Schistosoma mansoni, mitochondrial protein AMPylation, and the structural mechanisms of ion channels and endosomal recycling complexes.

Articles (14)

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2025

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2025

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2024

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2024

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2024

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2024

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2024

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2023

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2022

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2022

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2021

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2020

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2020

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2020

Collaborators (4)

youxing jiang

Professor

University of Texas Southwestern Medical Center

UNITED STATES

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Krzysztof Pawłowski

University of Texas Southwestern Medical Center

UNITED STATES

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Andrew Lemoff

University of Texas Southwestern Medical Center

UNITED STATES

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Ran Song

University of Texas Southwestern Medical Center

UNITED STATES

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Yan Han

Research Interests

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Articles (14)

A genome-scale drug discovery pipeline uncovers therapeutic targets and a unique p97 allosteric binding site in Schistosoma mansoni

A repurposed AMP binding domain reveals mitochondrial protein AMPylation as a regulator of cellular metabolism

Structural mechanism of proton conduction in otopetrin proton channel

Structural organization of the retriever–CCC endosomal recycling complex

TRPML1 gating modulation by allosteric mutations and lipids

TRPML1 gating modulation by allosteric mutations and lipids

Structural basis for Retriever-SNX17 assembly and endosomal sorting

Structural mechanisms of the human cardiac sodium-calcium exchanger NCX1

Structural mechanism of allosteric activation of TRPML1 by PI(3,5)P 2 and rapamycin

Structural mechanisms of assembly, permeation, gating, and pharmacology of native human rod CNG channel

Structural mechanisms of gating and selectivity of human rod CNGA1 channel

Structural insights into the Ca2+-dependent gating of the human mitochondrial calcium uniporter

Structural insights into the Ca2+-dependent gating of the human mitochondrial calcium uniporter

Cryo-EM structure of SWI/SNF complex bound to a nucleosome.

Collaborators (4)

youxing jiang

Krzysztof Pawłowski

Andrew Lemoff

Ran Song

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