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Yang-Xin Fu

professor

Tsinghua University

China

Research Interests

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Professors in Immunology

Articles (20)

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Collaborators (7)

Mark Mimee

Assistant Professor

University of Chicago

UNITED STATES

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Ralph Weichselbaum

University of Chicago Medicine

UNITED STATES

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Yidong Chen

Professor

University of Texas Health Science Center at San Antonio

UNITED STATES

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Alexei Tumanov

Associate Professor

University of Texas Health Science Center at San Antonio

UNITED STATES

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Burkhard Ludewig

University of Zurich & ETH Zurich

SWITZERLAND

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Yan Shi

Assistant Professor

University of Calgary

CANADA

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Yong Liang

associate professor

Tsinghua University

CHINA

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Yang-Xin Fu

Research Interests

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Articles (20)

IL-12 augments adoptive cell therapy by reshaping CD8+ T dynamics and broadening antitumor immunity

Engineered Probiotic Bifidobacterium for Tumor-Targeted Pancreatic Cancer Therapy

Fueling the fire: aspartate deficiency primes and fuels STING activation

Selective elimination of circulating effector CD8 T cells via LTβR blockade separates anti-CD137 efficacy from toxicity

Opportunities and challenges of targeting cGAS–STING in cancer

ILC3s promote intestinal tuft cell hyperplasia and anthelmintic immunity through RANK signaling

Anti–PD-L1–IFN-α–adjuvanted HBsAg vaccine overcomes HBV immune tolerance through targeting both DCs and macrophages

CARD9-dependent macrophage plasticity regulates effective fungal clearance

A next-generation anti-CTLA-4 probody mitigates toxicity and enhances anti-tumor immunity in mice

Membrane-IL12 adjuvant mRNA vaccine polarizes pre-effector T cells for optimized tumor control

Dual targeting OX40 and IL-2 receptor enhances antitumor activity through tumor-infiltrating Treg depletion and CD8+ T-cell proliferation

Eliciting antitumor immunity via therapeutic cancer vaccines

Orchestrating intratumoral DC-T cell immunity for enhanced tumor control via radiotherapy-activated TLR7/8 prodrugs in mice

TIM3-blockade synergizes with IL2 in alleviating intra-tumoral CD8+T cell exhaustion

Engineering cytokines for tumor-targeting and selective T cell activation

Metabolic reprograming mediated by tumor cell-intrinsic type I IFN signaling is required for CD47-SIRPα blockade efficacy

Anti-PD-1 cis-delivery of low-affinity IL-12 activates intratumoral CD8+T cells for systemic antitumor responses

Facts and Hopes on Chimeric Cytokine Agents for Cancer Immunotherapy

Promising Cytokine Adjuvants for Enhancing Tuberculosis Vaccine Immunity

Inactivation of TGF-β signaling in CAR-T cells

Collaborators (7)

Mark Mimee

Ralph Weichselbaum

Yidong Chen

Alexei Tumanov

Burkhard Ludewig

Yan Shi

Yong Liang

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