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Yang Yang

Jack and Barbara McCoy Associate Professor

Purdue University

United States

Research Interests

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Professors in United States Professors in Electrophysiology Electrophysiology professors in United States

Articles (13)

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2026

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2026

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2025

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2022

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2021

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2021

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2021

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2021

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2021

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2021

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2021

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2020

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2020

Collaborators (8)

Chongli Yuan

Professor

Purdue University

UNITED STATES

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Zhong-Yin Zhang

Purdue University

UNITED STATES

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Jingliang Zhang

Purdue University

UNITED STATES

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Long-Jun Wu

Professor and Founding Director

The University of Texas Health Science Center at Houston

UNITED STATES

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Fei Liu

Institute for Basic Research in Developmental Disabilities

UNITED STATES

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William Skarnes

Professor

Jackson Laboratory - Farmington

UNITED STATES

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Krishna Jayant

Assistant Professor

Purdue University

UNITED STATES

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Ranjie Xu

Assistant Professor

Purdue University

UNITED STATES

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Yang Yang

Research Interests

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Articles (13)

Human microglia in brain assembloids display region-specific diversity and respond to hyperexcitable neurons carrying SCN2A mutation

Precision medicine for sodium channelopathy-related autism and epilepsy

Alzheimer’s disease patient brain extracts induce multiple pathologies in novel vascularized neuroimmune organoids for disease modeling and drug discovery

Deficiency of autism-related Scn2a gene in mice disrupts sleep patterns and circadian rhythms.

Severe deficiency of the voltage-gated sodium channel Na<sub>V</sub>1.2 elevates neuronal excitability in adult mice.

Hyperexcitability and Pharmacological Responsiveness of Cortical Neurons Derived from Human iPSCs Carrying Epilepsy-Associated Sodium Channel Nav1.2-L1342P Genetic Variant.

Multi-Electrode Array of Sensory Neurons as an In Vitro Platform to Identify the Nociceptive Response to Pharmaceutical Buffer Systems of Injectable Biologics

Hydropathicity-based prediction of pain-causing NaV1.7 variants.

Non-extensitivity and criticality of atomic hydropathicity around a voltage-gated sodium channel's pore: a modeling study.

PKA-RIIβ autophosphorylation modulates PKA activity and seizure phenotypes in mice.

Generation and basic characterization of a gene-trap knockout mouse model of Scn2a with a substantial reduction of voltage-gated sodium channel Na<sub>v</sub> 1.2 expression.

Examining Sodium and Potassium Channel Conductances Involved in Hyperexcitability of Chemotherapy-Induced Peripheral Neuropathy: A Mathematical and Cell Culture-Based Study.

Deletion of Kv10.2 Causes Abnormal Dendritic Arborization and Epilepsy Susceptibility.

Collaborators (8)

Chongli Yuan

Zhong-Yin Zhang

Jingliang Zhang

Long-Jun Wu

Fei Liu

William Skarnes

Krishna Jayant

Ranjie Xu

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