Yasushi Kawaguchi

Professor

University of Tokyo

Japan

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About

Yasushi Kawaguchi is a Professor at The University of Tokyo in Japan. His research focuses on herpesvirus biology, with recent articles exploring viral activators, nuclear egress complexities, and mechanisms of viral immune evasion. His work contributes significantly to understanding the interactions and pathogenesis of herpes simplex virus and its implications for viral infection and replication.

Articles (20)

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2025

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2022

Collaborators (9)

Takara Nishiyama

Project Assistant Professor

Institute of Science Tokyo

JAPAN

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Hajime Hirase

Københavns Universitet

DENMARK

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Kouichi Kitamura

National Institute of Infectious Diseases

JAPAN

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Jun-ichiro Inoue

University of Tokyo

JAPAN

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Hideki Ogura

Assistant Professor

Hyogo medical university

JAPAN

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Hiroko Kozuka-Hata

Tokyo Metropolitan Institute of Medical Science

JAPAN

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Mizuki Yamamoto

University of Tokyo

JAPAN

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Masaaki Oyama

Tokyo Metropolitan Institute of Medical Science

JAPAN

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Shinobu Kitazume

JAPAN

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Yasushi Kawaguchi

Research Interests

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Articles (20)

Herpes simplex virus 1 evades APOBEC1-mediated immunity via its uracil-DNA glycosylase in mice

Identification of viral activators of the HSV-2 UL13 protein kinase

ESCRT-III is recruited by human herpesvirus 6A nuclear egress complex to promote nuclear egress of the nucleocapsid

Impact of the changes in substrate specificity of herpes simplex virus 1 protein kinase Us3 on viral infection in vitro and in vivo

Direct relationship between protein expression and progeny yield of herpes simplex virus 1

Regulatory mimicry of cyclin-dependent kinases by a conserved herpesvirus protein kinase

Unveiling the impact of simulated microgravity on HSV-1 infection, neuroinflammation, and endogenous retroviral activation in SH-SY5Y cells

Impact of the interaction between herpes simplex virus 1 ICP22 and FACT on viral gene expression and pathogenesis

Identification of a novel neurovirulence factor encoded by the cryptic orphan gene UL31.6 of herpes simplex virus 1

MYBBP1A is required for efficient replication and gene expression of herpes simplex virus 1

In Silico and In Vitro Evaluation of Some Amidine Derivatives as Hit Compounds towards Development of Inhibitors against Coronavirus Diseases

Brain‐specific glycosylation of protein tyrosine phosphatase receptor type Z (PTPRZ) marks a demyelination‐associated astrocyte subtype

Brain-specific glycosylation enzyme GnT-IX maintains levels of protein tyrosine phosphatase receptor PTPRZ, thereby mediating glioma growth PTPRZ glycosylation regulates glioma growth.

Dual impacts of a glycan shield on the envelope glycoprotein B of HSV-1: evasion from human antibodies in vivo and neurovirulence

Interferon regulatory factor 3 mediates effective antiviral responses to human coronavirus 229E and OC43 infection

Establishment of a system to quantify wild‐type herpes simplex virus–induced cell–cell fusion reveals a role of N‐glycosylation of HSV‐1 envelope glycoprotein B in cell–cell fusion

STING signalling is terminated through ESCRT-dependent microautophagy of vesicles originating from recycling endosomes

Dysfunctional Sars-CoV-2-M protein-specific cytotoxic T lymphocytes in patients recovering from severe COVID-19

Metalloproteinase-Dependent and TMPRSS2-Independent Cell Surface Entry Pathway of SARS-CoV-2 Requires the Furin Cleavage Site and the S2 Domain of Spike Protein

Redundant and Specific Roles of A-Type Lamins and Lamin B Receptor in Herpes Simplex Virus 1 Infection

Collaborators (9)

Takara Nishiyama

Hajime Hirase

Kouichi Kitamura

Jun-ichiro Inoue

Hideki Ogura

Hiroko Kozuka-Hata

Mizuki Yamamoto

Masaaki Oyama

Shinobu Kitazume

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