Yasuyuki Saito

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Associate Professor

Kobe University Graduate School of Medicine

Japan

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Yasuyuki Saito is an Associate Professor at Kobe University Graduate School of Medicine in Japan. His research focuses on cellular immunology, particularly in the context of red blood cells, macrophage interaction, and T cell survival. Recent studies by Professor Saito have explored critical pathways in cancer treatment and liver fibrosis, as well as advancements in hematopoietic stem cell transplantation diagnosis and therapy.

Recent Grants

Grant: Close

Elucidation of the immune control mechanism by the cell-to-cell signaling CD47-SIRPα system

Open Date: 2015-04-01

Close Date: 2018-03-31

Grant: Close

The role of SHPS-1 in dendritic cell-mediated autoimmune diseases

Open Date: 2009-01-01

Close Date: 2010-12-31

Grant: Close

Elucidation of a new control mechanism of autoimmune disease by CD47 over SHPS-1 system

Open Date: 2008-01-01

Close Date: 2009-12-31

Articles (20)

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2020

Collaborators (8)

Yoriaki KANEKO

Gunma University

JAPAN

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Hironobu Minami

JAPAN

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Yoshinori Imamura

Assistant Professor

Kobe University Hospital

JAPAN

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Naomi Kiyota

Associate Professor

Kobe University Hospital

JAPAN

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Mitsuhiro Ito

Professor

Kobe University Graduate School of Medicine

JAPAN

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Takashi Matozaki

Kobe University Graduate School of Medicine

JAPAN

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Yohei Funakoshi

Kobe University Hospital

JAPAN

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YOSHIAKI NAGATANI

Kobe University Hospital

JAPAN

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Yasuyuki Saito

Research Interests

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About

Recent Grants

Articles (20)

CD47 promotes RBC survival by preventing DC-mediated retention and macrophage-mediated phagocytosis of RBC in the spleen

Enhancing anti-EGFRvIII CAR T cell therapy against glioblastoma with a paracrine SIRPγ-derived CD47 blocker

CD47 promotes peripheral T cell survival by preventing dendritic cell–mediated T cell necroptosis

Response to <scp>mRNA SARS‐CoV</scp>‐2 vaccination evaluated by B‐cell receptor repertoire after tixagevimab/cilgavimab administration

Lysosomal cholesterol overload in macrophages promotes liver fibrosis in a mouse model of NASH.

THBS1-producing tumor-infiltrating monocyte-like cells contribute to immunosuppression and metastasis in colorectal cancer.

Early diagnosis of sinusoidal obstruction syndrome after hematopoietic stem cell transplantation, with modified diagnostic criteria including refractory thrombocytopenia.

Targeting of SIRPα as a potential therapy for Langerhans cell histiocytosis.

Global longitudinal strain is superior to ejection fraction for long-term follow-up after allogeneic hematopoietic stem cell transplantation

THBS1-producing tumor-infiltrating monocyte-like cells contribute to immunosuppression and metastasis in colorectal cancer

A Third Dose COVID-19 Vaccination in Allogeneic Hematopoietic Stem Cell Transplantation Patients

Promising Efficacy of a Third Dose of mRNA SARS-CoV-2 Vaccination in Patients Treated with Anti-CD20 Antibody Who Failed 2-Dose Vaccination

The Role of Type-2 Conventional Dendritic Cells in the Regulation of Tumor Immunity

Anticancer efficacy of monotherapy with antibodies to SIRPα/SIRPβ1 mediated by induction of antitumorigenic macrophages

The Safety and Immunogenicity of the BNT162b2 mRNA COVID-19 Vaccine in Japanese Patients after Allogeneic Stem Cell Transplantation

Global longitudinal strain is superior to ejection fraction for long-term follow-up after allogeneic hematopoietic stem cell transplantation.

Roles of Src family kinase, Ras, and mTOR signaling in intestinal epithelial homeostasis and tumorigenesis

BRAFV 600E or mutant MAP2K1 human CD34+ cells establish Langerhans cell–like histiocytosis in immune-deficient mice

Blockade of CD47 or SIRPα: a new cancer immunotherapy

SIRPα on CD11c+ cells induces Th17 cell differentiation and subsequent inflammation in the CNS in experimental autoimmune encephalomyelitis

Collaborators (8)

Yoriaki KANEKO

Hironobu Minami

Yoshinori Imamura

Naomi Kiyota

Mitsuhiro Ito

Takashi Matozaki

Yohei Funakoshi

YOSHIAKI NAGATANI

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