Yi-Jia Li

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Assistant Research Professor

Beckman Research Institute, City of Hope

United States

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About

Dr. Yi-Jia Li is an Assistant Research Professor at the Beckman Research Institute, City of Hope in the United States. His research focuses on ovarian cancer, specifically the roles of PD-L1 and STAT proteins in cancer progression and therapy resistance. Recent publications highlight innovative approaches in gene perturbation, targeting tumor metabolism, and enhancing antitumor immune responses.

Recent Grants

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Developing an effective targeted therapy for undifferentiated round cell sarcomas by directly targeting CIC-DUX4 fusion and Myc oncoproteins

Open Date: 2023-06-01

Close Date: 2024-06-01

Articles (9)

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2025

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2024

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2024

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2023

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2022

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2022

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2021

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2021

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2020

Collaborators (3)

Ji Eun Song

UNITED STATES

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Johannes Fahrmann

Assistant Professor

The University of Texas MD Anderson Cancer Center

UNITED STATES

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Toshikage Nagao

associate professor

Tokyo Medical and Dental University

JAPAN

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Yi-Jia Li

Research Interests

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About

Recent Grants

Articles (9)

A Critical Role of Intracellular PD-L1 in Promoting Ovarian Cancer Progression

Targeting PARG induces tumor cell growth inhibition and antitumor immune response by reducing phosphorylated STAT3 in ovarian cancer

A platform to deliver single and bi-specific Cas9/guide RNA to perturb genes in vitro and in vivo.

STAT proteins in cancer: orchestration of metabolism

Niraparib-induced STAT3 inhibition increases its antitumor effects

Fatty acid oxidation protects cancer cells from apoptosis by increasing mitochondrial membrane lipids

PARP Inhibition Activates STAT3 in Both Tumor and Immune Cells Underlying Therapy Resistance and Immunosuppression In Ovarian Cancer.

Potent antitumor effects of cell-penetrating peptides targeting STAT3 axis.

CD44 in Ovarian Cancer Progression and Therapy Resistance-A Critical Role for STAT3.

Collaborators (3)

Ji Eun Song

Johannes Fahrmann

Toshikage Nagao

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