Yi Zhang

Res Associate Professor

University of Rochester Medical Center

United States

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About

Dr. Yi Zhang is an Associate Professor at the University of Rochester Medical Center in the United States. His research focuses on the interaction between tumor microenvironments and hematopoiesis, particularly in the context of leukemogenesis and the immune response in lymphoid malignancies. Recent articles have explored topics such as the tumor infiltrating lymphocyte evaluation, spatial analysis of DNA damage responses, and innovative genetic engineering for hematopoietic stem cells.

Articles (11)

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2025

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2025

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2024

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2023

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2023

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2022

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2021

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2021

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2020

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2020

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2020

Collaborators (4)

James Palis

Professor

University of Rochester Medical Center

UNITED STATES

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Timm Schroeder

Professor for Cell Systems Dynamics

ETH Zürich

SWITZERLAND

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KONSTANTINOS KOKKALIARIS

Goethe University Frankfurt

GERMANY

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Archibald Perkins

Professor

University of Rochester

UNITED STATES

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Yi Zhang

Research Interests

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Articles (11)

Neighborhood clustering analysis to define epithelial–stromal interface for tumor infiltrating lymphocyte evaluation

Taurine from tumour niche drives glycolysis to promote leukaemogenesis

Multiplex imaging reveals spatially resolved <scp>DNA</scp>‐damage response neighborhoods in <scp><i>TP53</i></scp>‐mutated myelodysplastic neoplasms

Localization of DC-SIGN Expressing Cells in Follicular Lymphoma

Lymph node location and retention properties of DC‐SIGN engagement with the Immunoglobulin Oligomannoses of Follicular Lymphoma

Highly efficient Runx1 enhancer eR1-mediated genetic engineering for fetal, child and adult hematopoietic stem cells.

Mds1<sup>CreERT2</sup>, an inducible Cre allele specific to adult-repopulating hematopoietic stem cells.

<i>Mds1 CreERT2</i>-Based Lineage-Tracing Reveals Increasing Contributions of HSCs to Fetal Hematopoiesis and to Adult Tissue-Resident Macrophages in the Marrow

Live-animal imaging of native haematopoietic stem and progenitor cells.

Prdm3 and Prdm16 cooperatively maintain hematopoiesis and clonogenic potential.

MDS1-EVI1 Complex (MECOM) Activation Promotes Leukemic Stem Cell Quiescence By Upregulating CDKN1C/P57Kip2

Collaborators (4)

James Palis

Timm Schroeder

KONSTANTINOS KOKKALIARIS

Archibald Perkins

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