Yin-Huai Chen

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University of Oxford

United Kingdom

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Investigation of epigenetic and post-translational modifications in altered STAT3 function downstream of the GP130 and IL-10RB cytokine families.

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Articles (8)

Year:

2024

Year:

2021

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2021

Year:

2021

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2020

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2020

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2020

Year:

2020

Collaborators (9)

Stephen Sansom

University of Oxford

UNITED KINGDOM

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Holm Uhlig

Professor of Paediatric Gastroenterology

University of Oxford

UNITED KINGDOM

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Dirk Schmidt-Arras

Assistant Professor

AUSTRIA

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Andrei Chagin

University of Gothenburg

SWEDEN

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Jens Staal

Lecturer (90%)

Ghent University

BELGIUM

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Giedre Grigelioniene

SWEDEN

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Catherine Hawrylowicz

King’s College London

UNITED KINGDOM

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Eamonn Gaffney

University of Oxford

UNITED KINGDOM

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Dominik Aschenbrenner

University of Oxford

UNITED KINGDOM

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Yin-Huai Chen

Research Interests

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Contact this professor

Recent Grants

Articles (8)

The Human GP130 Cytokine Receptor and Its Expression—an Atlas and Functional Taxonomy of Genetic Variants

The induction of alpha-1 antitrypsin by vitamin D in human T cells is TGF-β dependent: a proposed anti-inflammatory role in airway disease

Inborn errors of IL-6 family cytokine responses.

Functional and structural analysis of cytokine-selective IL6ST defects that cause recessive hyper-IgE syndrome.

Deconvolution of monocyte responses in inflammatory bowel disease reveals an IL-1 cytokine network that regulates IL-23 in genetic and acquired IL-10 resistance.

A variant in IL6ST with a selective IL-11 signaling defect in human and mouse

Dominant-negative mutations in human IL6ST underlie hyper-IgE syndrome

Absence of GP130 cytokine receptor signaling causes extended Stüve-Wiedemann syndrome

Collaborators (9)

Stephen Sansom

Holm Uhlig

Dirk Schmidt-Arras

Andrei Chagin

Jens Staal

Giedre Grigelioniene

Catherine Hawrylowicz

Eamonn Gaffney

Dominik Aschenbrenner

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