Yizhou Dong

Professor

Icahn School of Medicine at Mount Sinai

United States

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About

Yizhou Dong is a Professor at the Icahn School of Medicine at Mount Sinai in the United States. His research focuses on antibody engineering, mRNA therapeutics, and nanotechnology-based vaccines, with recent publications addressing the blood-brain barrier, lipid nanoparticles, and biomaterials for cell therapy. He is dedicated to advancing the clinical translation of mRNA technologies and exploring challenges in the field.

Articles (16)

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2025

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Ohio State University

UNITED STATES

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Yizhou Dong

Research Interests

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About

Articles (16)

An mRNA-based broad-spectrum antiviral inspired by ISG15 deficiency protects against viral infections in vitro and in vivo

Lipid Nanoparticles for mRNA Delivery in Brain via Systemic Administration

Antibody Engineering for Receptor-Mediated Transcytosis Across the Blood–Brain Barrier

Advances in the rational design of ionizable lipids for mRNA therapeutics

RNA chemistry and therapeutics

Engineering LNPs with polysarcosine lipids for mRNA delivery

Nanotechnology-based mRNA vaccines

Advancements of in vitro transcribed mRNA (IVT mRNA) to enable translation into the clinics

Biomaterials for in situ cell therapy

Opportunities and Challenges in mRNA Therapeutics

Author Correction: Lipid nanoparticles for mRNA delivery (Nature Reviews Materials, (2021), 6, 12, (1078-1094), 10.1038/s41578-021-00358-0)

Delivery of CRISPR-Cas9 system for screening and editing RNA binding proteins in cancer

Recent advances of biomaterials in stem cell therapies

Biomimetic nanoparticles deliver mRNAs encoding costimulatory receptors and enhance T cell mediated cancer immunotherapy.

Advances of nanomaterials‐based strategies for fighting against COVID‐19

Computational and Experimental Approaches to Investigate Lipid Nanoparticles as Drug and Gene Delivery Systems

Collaborators (6)

Jeffrey Johnson

Lior Zangi

drew weissman

Chang Wang

Roosheel Patel

William E. Carson, III

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