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Yong-Jie Zhang

Associate Professor

University of Miami

United States

Research Interests

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Articles (18)

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2026

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2023

Collaborators (17)

Yi Zeng

Stanford University

UNITED STATES

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Ying Hao

National Institutes of Health

UNITED STATES

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Yuka Koike

Assistant professor

Niigata University

JAPAN

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Jonathan Rohrer

University College London

UNITED KINGDOM

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David Sanders

Assistant Professor (Tenure-Track)

University of Texas Southwestern Medical Center

UNITED STATES

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Richard Giadone

Harvard University

UNITED STATES

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Matthew Keuss

Senior Research Fellow

University College London

UNITED KINGDOM

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Gregory Day

Associate Professor, Consultant

Mayo Clinic

UNITED STATES

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Dylan Neel

Harvard University

UNITED STATES

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Mercedes Prudencio

Associate Professor - pending rank

University of Miami Health System

UNITED STATES

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Lei S Qi

Associate Professor

Stanford University

UNITED STATES

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Nathan Staff

Mayo Clinic

UNITED STATES

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Jinyoung Park

Research professor

Korea University

SOUTH KOREA

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Sarah Kargbo-Hill

Assistant Professor

University of Michigan

UNITED STATES

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Anna-Leigh Brown

University College London

UNITED KINGDOM

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Aaron Gitler

Stanford University

UNITED STATES

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Manolis Maragkakis

Earl Stadtman Principal Investigator

National Institute on Aging

UNITED STATES

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Yong-Jie Zhang

Research Interests

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Articles (18)

PPAR-Delta Agonist Therapies Did Not Rescue Hallmark Disease Phenotypes in Two Sets of Preclinical Trials in ALS TDP-43 and C9orf72 Model Mice

TDP-43-mediated alternative polyadenylation is associated with a reduction in VPS35 and VPS29 expression in frontotemporal dementia

Preclinical Evaluation of the Assembly Modulator PAV-615 in a Mouse Model of <i>C9orf72</i>-Associated ALS/FTD

CRISPR activation of the ribosome-associated quality control factor ASCC3 ameliorates fragile X syndrome phenotypes in mice

Dual-targeting CRISPR-CasRx reduces C9orf72 ALS/FTD sense and antisense repeat RNAs in vitro and in vivo

Endolysosomal dysfunction impairs proteostasis and induces neurodegeneration in vivo

TDP-43 Cryptic RNAs in Perry Syndrome: Differences across Brain Regions and TDP-43 Proteinopathies

Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD.

TMEM106B core deposition associates with TDP-43 pathology and is increased in risk SNP carriers for frontotemporal dementia

Correction to: HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases (Molecular Neurodegeneration, (2024), 19, 1, (29), 10.1186/s13024-024-00718-8)

Generation and characterization of monoclonal antibodies against pathologically phosphorylated TDP-43

HDGFL2 cryptic protein: a portal to detection and diagnosis in neurodegenerative disease

HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases

Poly(GR) interacts with key stress granule factors promoting its assembly into cytoplasmic inclusions

TDP-43 and other hnRNPs regulate cryptic exon inclusion of a key ALS/FTD risk gene, UNC13A

Gasdermin-E mediates mitochondrial damage in axons and neurodegeneration

Inflammasome-Mediated Neuronal-Microglial Crosstalk: a Therapeutic Substrate for the Familial C9orf72 Variant of Frontotemporal Dementia/Amyotrophic Lateral Sclerosis

The endolysosomal pathway and ALS/FTD

Collaborators (17)

Yi Zeng

Ying Hao

Yuka Koike

Jonathan Rohrer

David Sanders

Richard Giadone

Matthew Keuss

Gregory Day

Dylan Neel

Mercedes Prudencio

Lei S Qi

Nathan Staff

Jinyoung Park

Sarah Kargbo-Hill

Anna-Leigh Brown

Aaron Gitler

Manolis Maragkakis

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