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Yoshihiro Tokudome

Professor

Saga University

Japan

Research Interests

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Professors in Japan Professors in Biochemistry Biochemistry professors in Japan

About

Yoshihiro Tokudome is a Professor at Saga University in Japan. His research focuses on skin health and the effects of various compounds on dermatological functions, as evidenced by his recent articles on topics such as hyaluronic acid and its impact on skin barriers, as well as the influence of environmental factors on keratinocyte behavior. His work also explores innovative approaches to cosmetic applications and skin microbiota interactions.

Articles (19)

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2026

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2020

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2020

Collaborators (3)

Hiroshi Kitagaki

Professor

Saga Daigaku

JAPAN

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Munehiro Tanaka

Saga University

JAPAN

View details

Madoka Kage

Assistant Professor

Josai University

JAPAN

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Yoshihiro Tokudome

Research Interests

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About

Articles (19)

Rakkyo (Allium chinense)-Derived Fructan Stimulates Collagen and Hyaluronan Synthesis in Human Dermal Fibroblasts

Orally Delivered Hyaluronic Acid Tetrasaccharide Improves Skin Barrier Function in UVB-Irradiated Mice: A Bioactive Approach for Cosmetic and Nutritional Applications

Effect of low humidity on the barrier functions of keratinocytes in a reconstructed human epidermal model

2 kDa Hyaluronic Acid Reduces Blemishes and Sagging in Human Facial Skin

Influence of Radical Generation and Elimination on Sebum Production of Hamster Sebaceous Gland Cells

Dual Regulation of Corneodesmosome Formation by Shotokuseki Extract Enhances Skin Barrier Homeostasis

Lactobacillus gasseri Decreases p-Cresol Levels in Serum and Cecum and Improves Skin Characteristics in Mice Fed with Tyrosine-Rich Diets

Synergistic effect of cerium chloride and calcium chloride alters calcium signaling in keratinocytes to promote epidermal differentiation

Ionic composition of Shotokuseki extract alters cell differentiation and lipid metabolism in three-dimensional cultured human epidermis

A Trial for the Construction of a Cosmetic Pattern Map Considering Their Effects on Skin Microbiota—Principal Component Analysis of the Effects on Short-Chain Fatty Acid Production by Skin Microbiota Staphylococcus epidermidis

Sphingomyelin reduces melanogenesis in murine B16 melanoma cells through indirect suppression of tyrosinase

Fermented Cosmetics and Metabolites of Skin Microbiota—A New Approach to Skin Health

The ion balance of Shotokuseki extract promotes filaggrin fragmentation and increases amino acid production and pyrrolidone carboxylic acid content in three-dimensional cultured human epidermis

Shotokuseki Extract Promotes Keratinocyte Differentiation Even at a Low Calcium Concentration

Role of collagen degradation pathway in sphingomyelin synthase 2-deficient mouse skin

Effect of Lactic Fermentation Products on Human Epidermal Cell Differentiation, Ceramide Content, and Amino Acid Production

Pathogenic and Compensatory Mechanisms in Epidermis of Sphingomyelin Synthase 2-Deficient Mice

Nanoparticulation of hyaluronic acid: A new skin penetration enhancing polyion complex formulation: mechanism and future potential

Synthesis of Resorcinol Derivatives and their Effects on Melanin Production

Collaborators (3)

Hiroshi Kitagaki

Munehiro Tanaka

Madoka Kage

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