Yu Xia

Professor of Bioengineering

McGill University

Canada

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Yu Xia is a Professor of Bioengineering at McGill University, Canada (+11). His research focuses on the interactions within protein networks, specifically the evolutionary aspects of protein-protein interactions and their implications in areas such as viral targeting and genetic mutations. Recent publications include studies on the relationship between interfacial overlap and functional divergence as well as the impact of disorder-order switching on protein sequence evolution.

Articles (18)

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2025

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2025

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2025

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2025

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2024

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2024

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2022

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2021

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2021

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2021

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2021

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2021

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2020

Collaborators (2)

Amine Kamen

Professor

McGill University Faculty of Engineering

CANADA

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Ioannis Ragoussis

Professor, Head of Genome Sciences

McGill University

CANADA

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Yu Xia

Research Interests

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Articles (18)

The relationship between interfacial overlap and functional divergence in the yeast protein-protein interaction network

The Impact of Disorder-Order Switching on Protein Sequence Evolution.

A quantitative comparison of the deleteriousness of missense and nonsense mutations using the structurally resolved human protein interactome

Virus targeting as a dominant driver of interfacial evolution in the structurally resolved human-virus protein-protein interaction network.

SSRAAI: Learning sequence and structural representations to predict antibody-antigen interactions

Structure-guided evolutionary analysis of interactome network rewiring at single residue resolution in yeasts.

Predicting depression risk in early adolescence via multimodal brain imaging.

Comparative Transcriptomic Analyses of a Vero Cell Line in Suspension versus Adherent Culture Conditions

From functional genomics of vero cells to CRISPR‐based genomic deletion for improved viral production rates

Overview of recent advances in Vero cells genomic characterization and engineering for high‐throughput vaccine manufacturing

Structural determinants of yeast protein-protein interaction interface evolution at the residue level

Are transient protein-protein interactions more dispensable?

Haplotype-resolved de novo assembly of the Vero cell line genome

Principal component analysis of alpha-helix deformations in transmembrane proteins.

Mutation Edgotype Drives Fitness Effect in Human

Structural Profiling of Bacterial Effectors Reveals Enrichment of Host-Interacting Domains and Motifs

Quantifying evolutionary importance of protein sites: A Tale of two measures.

A pooled genome-wide screening strategy to identify and rank influenza host restriction factors in cell-based vaccine production platforms.

Collaborators (2)

Amine Kamen

Ioannis Ragoussis

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