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Yuanliang Zhai

Associate Professor

The Hong Kong University of Science and Technology

Hong Kong

Research Interests

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Professors in Cell Biology

Articles (17)

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2026

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2026

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2025

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2025

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2023

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2023

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2023

Collaborators (7)

Jason Wong

Professor

The University of Hong Kong

HONG KONG

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Chaogu Zheng

Associate Professor

The University of Hong Kong

HONG KONG

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Qian Zhao

Associate Professor

The Hong Kong Polytechnic University

HONG KONG

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Stephen West

Senior Group Leader

The Francis Crick Institute

UNITED KINGDOM

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Toyotaka Ishibashi

Associate Professor

The Hong Kong University of Science and Technology

CHINA

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I-Ming Hsing

Department Head

The Hong Kong University of Science and Technology

HONG KONG

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Chun-Long Chen

Université PSL

FRANCE

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Yuanliang Zhai

Research Interests

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Articles (17)

Distinct roles of MCM2-7 subunits in replication licensing in human cells

DNA-guided CRISPR–Cas12a effectors for programmable RNA recognition and cleavage

ANKLE1 processes chromatin bridges by cleaving mechanically stressed DNA

MCM5 UFMylation regulates replication origin firing and fork progression

H2B.W2, a spermatocyte-specific histone variant, disrupts nucleosome stability, and reduces chromatin compaction

Tubulin isotypes of C. elegans harness the mechanosensitivity of the lattice for microtubule luminal accessibility

DNA bending mediated by ORC is essential for replication licensing in budding yeast

Tubulin acetyltransferases access and modify the microtubule luminal K40 residue through anchors in taxane-binding pockets

Testis-specific H2B.W1 disrupts nucleosome integrity by reducing DNA–histone interactions

Assembly and activation of replicative helicases at origin DNA for replication initiation

Replication licensing regulated by a short linear motif within an intrinsically disordered region of origin recognition complex

Parental histone transfer caught at the replication fork

The human pre-replication complex is an open complex

The Origin Recognition Complex: From Origin Selection to Replication Licensing in Yeast and Humans

Synergism between CMG helicase and leading strand DNA polymerase at replication fork

Menin “reads” H3K79me2 mark in a nucleosomal context

DDK promotes DNA replication initiation: Mechanistic and structural insights

Collaborators (7)

Jason Wong

Chaogu Zheng

Qian Zhao

Stephen West

Toyotaka Ishibashi

I-Ming Hsing

Chun-Long Chen

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