Yuesheng Zhang

Professor

Virginia Commonwealth University

United States

Research Interests

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About

Yuesheng Zhang is a Professor at Virginia Commonwealth University in the United States. His research focuses on cancer treatment, specifically the roles of receptor tyrosine kinases, the tumor suppressor p53, and the effects of dietary compounds from cruciferous vegetables on cancer progression. Recent publications highlight his investigations into targeted therapies for HER2-positive breast cancer and the mechanisms of therapy resistance in various cancer models.

Articles (10)

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2025

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2024

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2023

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2023

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2022

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2022

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2022

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2021

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2020

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2020

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Yuesheng Zhang

Research Interests

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About

Articles (10)

The multifunctional proline-rich domain of p53 tumor suppressor.

Targeted dual degradation of HER2 and EGFR obliterates oncogenic signaling, overcomes therapy resistance, and inhibits metastatic lesions in HER2-positive breast cancer models

Targeting Epidermal Growth Factor Receptor for Cancer Treatment: Abolishing both Kinase-Dependent and Kinase-Independent Functions of the Receptor

Associations of dietary isothiocyanate exposure from cruciferous vegetable consumption with recurrence and progression of non-muscle-invasive bladder cancer: findings from the Be-Well Study.

Depleting receptor tyrosine kinases EGFR and HER2 overcomes resistance to EGFR inhibitors in colorectal cancer.

Single-Cell Analyses of a Novel Mouse Urothelial Carcinoma Model Reveal a Role of Tumor-Associated Macrophages in Response to Anti-PD-1 Therapy.

A Presurgical-Window Intervention Trial of Isothiocyanate-Rich Broccoli Sprout Extract in Patients with Breast Cancer.

Loss of peptidase D binding restores the tumor suppressor functions of oncogenic p53 mutants

Effects of cooking methods on total isothiocyanate yield from cruciferous vegetables.

The root cause of drug resistance in HER2-positive breast cancer and the therapeutic approaches to overcoming the resistance.

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