Yuki Mochida

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Junior Associate Professor

Tokyo Medical and Dental University

Japan

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About

Yuki Mochida is a Junior Associate Professor at Tokyo Medical and Dental University in Japan. His research focuses on innovative approaches to mRNA delivery systems and cancer immunotherapy, as evidenced by his recent publications on polycation enhancement of mRNA stability, tumor-targeting polymeric structures, and mRNA vaccine designs. Professor Mochida's work contributes significantly to advancing therapeutic strategies for cancer treatment and viral infections through novel nanocarrier technologies.

Recent Grants

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KAKENHI, Grant-in-Aid for Scientific Research (B)

Open Date: 2022-04-01

Close Date: 2026-03-01

Grant: Close

The Hattori Hokokai Foundation Research Grant

Open Date: 2021-10-01

Close Date: 2022-12-01

Grant: Close

KAKENHI, Grant-in-Aid for Fostering Joint International Research (B)

Open Date: 2021-10-01

Close Date: 2025-03-01

Grant: Close

COI collaborative research fund for young researchers

Open Date: 2021-04-01

Close Date: 2022-03-01

Grant: Close

KAKENHI, Grant-in-Aid for Scientific Research (A)

Open Date: 2021-04-01

Close Date: 2024-03-01

Articles (18)

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2025

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2021

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2021

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2021

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2021

Collaborators (17)

Satoshi Uchida

Tokyo Medical and Dental University

JAPAN

Yuki Mochida

Research Interests

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About

Recent Grants

Articles (18)

Poly(sarcosine) and Poly(2-ethyl-2-oxazoline) Tethered To mRNA Provide Stealth Properties To mRNA Polyplexes

Secondary Structure-Guided Assembly of Uniform Disk-Like Polymeric Micelles Incorporating Hydrophobic Platinum Drugs for Improved Tumor Targeting

Polycations Improve Intracellular Stability of mRNA Delivered Using Lipid Nanoparticles for Prolonged Protein Expression

Immunotherapy using allogenic NK cells downregulates mitochondrial-related genes and inhibits the OXPHOS system of malignant meningioma

mRNA vaccine designs for optimal adjuvanticity and delivery

Size-Dependent Glioblastoma Targeting by Polymeric Nanoruler with Prolonged Blood Circulation

Poly(ethylene Glycol) (PEG)-OligoRNA Hybridization to mRNA Enables Fine-Tuned Polyplex PEGylation for Spleen-Targeted mRNA Delivery

Selective Intracellular Delivery of Antibodies in Cancer Cells with Nanocarriers Sensing Endo/Lysosomal Enzymatic Activity

Terbium-Rose Bengal Coordination Nanocrystals-Induced ROS Production under Low-Dose X-rays in Cultured Cancer Cells for Photodynamic Therapy

Terbium-Rose Bengal Coordination Nanocrystals-Induced ROS Production under Low-Dose X-rays in Cultured Cancer Cells for Photodynamic Therapy

Effective mRNA Protection by Poly(L-Ornithine) Synergizes with Endosomal Escape Functionality of a Charge-Conversion Polymer Toward Maximizing mRNA Introduction Efficiency

Changeable net charge on nanoparticles facilitates intratumor accumulation and penetration.

Changeable net charge on nanoparticles facilitates intratumor accumulation and penetration

Effective mRNA Protection by Poly(l-ornithine) Synergizes with Endosomal Escape Functionality of a Charge-Conversion Polymer toward Maximizing mRNA Introduction Efficiency

Conjugation of glucosylated polymer chains to checkpoint blockade antibodies augments their efficacy and specificity for glioblastoma

Conjugation of glucosylated polymer chains to checkpoint blockade antibodies augments their efficacy and specificity for glioblastoma

Poly-ion complex micelle effectively delivers CoA-conjugated CPT1A inhibitors to modulate lipid metabolism in brain cells

Poly-ion complex micelles effectively deliver CoA-conjugated CPT1A inhibitors to modulate lipid metabolism in brain cells

Collaborators (17)

Satoshi Uchida

Yuto Honda

HYUN JIN KIM

West Kristian Paraiso

Kazunori Kataoka

Tsutomu Nakazawa

Yutaka Miura

Joachim F. R. Van Guyse

Mitsuru NAITO

Shigehito Osawa

Takahiro Nomoto

Hidetomo Yokoo

Li Junjie

Yasutaka Anraku

DEBABRATA MAITI

Kanjiro Miyata

Hiroyasu Takemoto

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