Yukihiro Kohara

Assistant professor

University of Tokyo

Japan

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About

Yukihiro Kohara is an Assistant Professor at Tokyo University of Science, Japan. His research areas encompass cellular differentiation and signaling pathways, particularly focusing on osteoclast differentiation, macrophage roles in bone regeneration, and the pathogenesis of diabetic nephropathy. Recent publications highlight his work on RANKL-induced osteoclast differentiation, the interplay between hedgehog signaling and tumor development, and the impact of oxidative stress on renal health.

Articles (8)

Year:

2024

Year:

2022

Year:

2022

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2021

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2020

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2020

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2020

Year:

2020

Collaborators (3)

Sohei Kitazawa

Professor and Chairman

Ehime University Graduate School of Medicine

JAPAN

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Tadayoshi Hayata

JAPAN

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Yuuki Imai

Professor

JAPAN

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Yukihiro Kohara

Research Interests

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Articles (8)

Ctdnep1 phosphatase is required for negative regulation of RANKL-induced osteoclast differentiation in RAW264.7 cells

Macrophages are requisite for angiogenesis of type H vessels during bone regeneration in mice

Novel animal model of soft tissue tumor due to aberrant hedgehog signaling activation in pericyte lineage

RANK- NFATc1 signaling forms positive feedback loop on rank gene expression via functional NFATc1 responsive element in rank gene promoter

Hedgehog inhibitors suppress osteoclastogenesis in in vitro cultures, and deletion of SMO in macrophage/osteoclast lineage prevents age-related bone loss

Knockdown of Lrp1 in RAW264 cells inhibits osteoclast differentiation and osteoclast-osteoblast interactions in vitro

Localization of DLL1- and NICD-positive osteoblasts in cortical bone during postnatal growth in rats

New insights into the pathogenesis of diabetic nephropathy: Proximal renal tubules are primary target of oxidative stress in diabetic kidney

Collaborators (3)

Sohei Kitazawa

Tadayoshi Hayata

Yuuki Imai

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