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Yuriy Karpenko

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associate professor

zaporizhzhia state medical and pharmaceutical university

Ukraine

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Professors in Organic Chemistry

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Hybrid compounds of 1,2,4-triazole and orotic acid with radioprotective, wound-healing, and regenerative properties for the needs of the civilian population and the Armed Forces of Ukraine

Open Date: 2026-04-01

Close Date: 2026-11-01

Articles (20)

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Collaborators (13)

Oleksandr Panasenko

Head of Department

zaporizhzhia state medical and pharmaceutical university

UKRAINE

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Kateryna Miedviedieva

Lecturer

zaporizhzhia state medical and pharmaceutical university

UKRAINE

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Jyrki Heinämäki

Professor

University of Tartu

ESTONIA

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Daria Safronova

Associate Professor

zaporizhzhia state medical and pharmaceutical university

UKRAINE

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Volodymyr Nahornyi

Associate Professor

zaporizhzhia state medical and pharmaceutical university

UKRAINE

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Svitlana Vasyuk

Professor

zaporizhzhia state medical and pharmaceutical university

UKRAINE

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Liudmyla Kucherenko

Professor, Head of the Department of Pharmaceutical, Organic and Bioorganic Chemistry

zaporizhzhia state medical and pharmaceutical university

UKRAINE

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Ain Raal

Professor of Pharmacognosy

University of Tartu

ESTONIA

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Anastasiia Donchenko

Senior Lecturer

zaporizhzhia state medical and pharmaceutical university

UKRAINE

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Oleh M. Koshovyi

Professor

zaporizhzhia state medical and pharmaceutical university

UKRAINE

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Bogdan Gutyj

Head of the Mykhailo Demchuk Department of Hygiene, Sanitation and General Veterinary Prevention

UKRAINE

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Anastasiia Khilkovets

Associate Professor

zaporizhzhia state medical and pharmaceutical university

UKRAINE

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Andrii Gotsulia

Doctor of Pharmaceutical Sciences, Associate Professor

zaporizhzhia state medical and pharmaceutical university

UKRAINE

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Yuriy Karpenko

Research Interests

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Articles (20)

Orotic Acid–1,2,4-Triazole Hybrids as Potential MMP-2,9 Modulating Wound-Healing Agents: Synthesis, Molecular Docking and Biological Evaluation

Spectrophotometric determination of 2-[5-(furan-2-yl)-4-phenyl-4n-1,2,4-triazol-3-ylthio]-1-(4-chlorophenylethanone)

Anti-Inflammatory and Antimicrobial Activities of Extracts Developed from <i>Symphytum officinale</i> Leaves, Flowers, and Roots: Experimental Evaluation and Molecular Docking Study

Novel 1,2,4‐Triazole–Thiopyrimidine Hybrids as COX‐2 Inhibitors: Synthesis, ADME Profiling, Antioxidant Activity, and Molecular Docking

Hypolipidemic activity in a series of new hybrids of orotic acid and 1,2,4-triazole

ВИКЛИКИ ТА ІННОВАЦІЇ У ВИКЛАДАННІ ЗАГАЛЬНОЇ ТА НЕОРГАНІЧНОЇ ХІМІЇ В УМОВАХ ПАНДЕМІЇ COVID-19 ТА ВІЙНИ (2021–2025 РР.) НА КАФЕДРІ ТОКСИКОЛОГІЧНОЇ ТА НЕОРГАНІЧНОЇ ХІМІЇ

Design, synthesis, molecular docking, and antioxidant properties of a series of new S-derivatives of ((1,2,4-triazol-3(2H)-yl)methyl)thiopyrimidines

Анальгезуюча ефективність нових похідних 1,2,4-триазолу в експериментальній моделі вісцерального болю: перспективи військово-медичного застосування

Quantum-chemical assessment of the antioxidant activity of 6-(4-R-5-mercapto-4H-1,2,4-triazol-3-yl)-pyrimidine-2,4(1H,3H)-dione derivatives: thermochemistry

The Development and Theoretical Examination of Hplc-Ms Determination Method For A Novel Veterinary Drug Tryfuzol-Neo 1% In Meat And Animal Organs

LC-ESI-MS analysis of 1,2,4-triazole derivatives with various alkyl and aromatic substituents

Synthesis and Tactics of Organic Synthesis of 6-(5-mercapto-4R-4H-1,2,4-triazol-3-YL)pyrimidine-2,4(1H,3H)-dione Derivatives

Synthesis, chemical properties and search for molecular descriptors of the fungicidal activity of new hybrids of 1,2,4-triazole(1,3,4-oxadiazole) bearing a pyrimidine fragment

4-phenyl-5-((pyrimidin-2-ylthio)methyl)-1,2,4-triazole-3-thiol as a platform for the synthesis of unsymmetrical disulfides

In silico study of the anti-inflammatory potential of new thiopyrimidine derivatives with 1,2,4-triazole as inhibitors of key inflammatory targets

DFT analysis of the [3 + 2] heterocyclization reaction of ((1,2,4-triazole(1,3,4-oxadiazole)-3(2)-yl)methyl)thiopyrimidines

Evaluation of the hypoglycemic potential of 6-(4-ethyl-5-mercapto-4H-1,2,4-triazol-3-yl)pyrimidine-2,4(1H,3H)-dione derivatives

Cytotoxic potential of novel triazole-based hybrids: design, synthesis, in silico evaluation, and in vitro assessment against cancer cell lines

Mechanochemical Nickel-Catalyzed Suzuki-Miyaura Cross-Coupling of Phenol-Derived Cyanate Esters

Monitoring the properties of 1,2,4-triazole derivatives for the development of original antimicrobial drugs,Моніторинг властивостей похідних 1,2,4-тріазолу щодо створення оригінальних антимікробних препаратів

Collaborators (13)

Oleksandr Panasenko

Kateryna Miedviedieva

Jyrki Heinämäki

Daria Safronova

Volodymyr Nahornyi

Svitlana Vasyuk

Liudmyla Kucherenko

Ain Raal

Anastasiia Donchenko

Oleh M. Koshovyi

Bogdan Gutyj

Anastasiia Khilkovets

Andrii Gotsulia

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