Zdenek Vavrina

Institute of Organic Chemistry and Biochemistry

Czech Republic

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Articles (7)

Year:

2023

Year:

2023

Year:

2023

Year:

2022

Year:

2022

Year:

2021

Year:

2021

Collaborators (4)

Zahra Aliakbar Tehrani

Institute of Biotechnology

CZECH REPUBLIC

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Pavla Perlíková

University of Chemistry and Technology

CZECH REPUBLIC

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Martin Klima

Institute of Organic Chemistry and Biochemistry

CZECH REPUBLIC

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Milan Kožíšek

Institute of Organic Chemistry and Biochemistry

CZECH REPUBLIC

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Zdenek Vavrina

Research Interests

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Articles (7)

Vinylphosphonate-based cyclic dinucleotides enhance STING-mediated cancer immunotherapy

Development and Characterization of a Chronic Hepatitis B Murine Model With a Mutation in the START Codon of an HBV Polymerase

Synthetic Stimulator of Interferon Genes (STING) Agonists Induce a Cytokine-Mediated Anti-Hepatitis B Virus Response in Nonparenchymal Liver Cells

Design, Synthesis, and Biochemical and Biological Evaluation of Novel 7-Deazapurine Cyclic Dinucleotide Analogues as STING Receptor Agonists

5′-Phosphonate modified oligoadenylates as potent activators of human RNase L

Protein-Ligand Interactions in the STING Binding Site Probed by Rationally Designed Single-Point Mutations: Experiment and Theory.

Enzymatic Synthesis of 3′–5′, 3′–5′ Cyclic Dinucleotides, Their Binding Properties to the Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity Correlations

Collaborators (4)

Zahra Aliakbar Tehrani

Pavla Perlíková

Martin Klima

Milan Kožíšek

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