Zhichao Fan

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Assistant Professor

University of Connecticut Health Center

United States

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About

Zhichao Fan is an Assistant Professor at the University of Connecticut Health Center in the United States. His research areas include monocyte adhesion mechanisms, integrin biology, and the regulation of immune cell functions through novel technological approaches. Recent publications highlight his work on CFTR's role in integrin clustering, the influence of Gpx4 on NKT cell homeostasis, and advancements in microfluidics for thrombus profiling in relation to hypertension and aging.

Recent Grants

Grant: Close

Molecular mechanism and preclinical translation of beta2 integrin auto-inhibition on neutrophil arrest and inflammation

Open Date: 2019-04-01

Close Date: 2024-02-29

Grant: Close

Impact of beta2 integrin auto-inhibition on neutrophil arrest and inflammation

Open Date: 2018-07-01

Close Date: 2021-06-01

Grant: Close

Molecular control of beta2 integrin activation, neutrophil adhesion and inflammation

Open Date: 2016-07-01

Close Date: 2018-06-01

Grant: Close

Monitor the metastasis of hepatocellular carcinoma by in vivo flow cytometry and intravital microscopy

Open Date: 2010-06-01

Close Date: 2013-06-01

Articles (20)

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2025

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2021

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2021

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2020

Collaborators (15)

Jennifer Dan

Assistant Professor

University of California, San Diego

UNITED STATES

Zhichao Fan

Research Interests

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About

Recent Grants

Articles (20)

Nanoscopy reveals integrin clustering reliant on kindlin-3 but not talin-1.

CFTR dictates monocyte adhesion by facilitating integrin clustering but not activation.

Monitoring Circulating Myeloid Cells in Peritonitis with an In Vivo Imaging Flow Cytometer

Gpx4 Regulates Invariant NKT Cell Homeostasis and Function by Preventing Lipid Peroxidation and Ferroptosis

UBXN3B is crucial for B lymphopoiesis.

UBXN9 governs GLUT4-mediated spatial confinement of RIG-I-like receptors and signaling.

Multi-parametric thrombus profiling microfluidics detects intensified biomechanical thrombogenesis associated with hypertension and aging.

A Flow Cytometry-Based High-Throughput Technique for Screening Integrin-Inhibitory Drugs.

How does alendronate affect orthodontic tooth movement in osteogenesis imperfecta: an in vivo study on a mice model

IL-2 can signal via chemokine receptors to promote regulatory T cells' suppressive function.

Real-Time Measurement of the Mitochondrial Bioenergetic Profile of Neutrophils.

Bone Marrow Transplantation Rescues Monocyte Recruitment Defect and Improves Cystic Fibrosis in Mice

Olfactory receptor 2 in vascular macrophages drives atherosclerosis by NLRP3-dependent IL-1 production

Direct Binding of Rap1 to Talin1 and to MRL Proteins Promotes Integrin Activation in CD4+ T Cells

Galectin 3 enhances platelet aggregation and thrombosis via Dectin-1 activation: a translational study

Integrin Regulators in Neutrophils

Elongated neutrophil-derived structures are blood-borne microparticles formed by rolling neutrophils during sepsis

β2 integrin activation and signal transduction in leukocyte recruitment

Distinct integrin activation pathways for effector and regulatory T cell trafficking and function

Imaging of the immune system – towards a subcellular and molecular understanding

Collaborators (15)

Jennifer Dan

Yunfeng Chen

HOLLY VAN REMMEN

Narcis Popescu

Allan Sun

Shivam Mehta

Alexandre Gingras

Mark Ginsberg

Marco Orecchioni

Kepeng Wang

Zbigniew Mikulski

Lai Wen

Yunmin Jung

Ryosuke Saigusa

Sumit Yadav

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