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Zhiwei Chen

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Director, Tenured Chair Professor and Endowed Professor of Suen Chi-Sun Professorship in Clinical Science

The University of Hong Kong

Hong Kong

Research Interests

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Professors in Immunology

Recent Grants

Grant: Close

A Novel Therapeutic AAV-vectored Bi-Specific Neutralizing Antibody against HIV/AIDS

Open Date: 2018-12-31

Close Date: 2019-06-30

Grant: Close

A Novel PD1-based Vaccine for HIV/AIDS Immunotherapy

Open Date: 2018-03-01

Close Date: 2020-08-31

Grant: Close

Immuno Cure Limited is a biomedical research and development company focusing on the development of a PD1 - based vaccine, which may potentially offer a functional cure to AIDS patients by vaccine-induced immune protection under discontinued drug treatment.

Open Date: 2015-04-01

Close Date: 2016-03-31

Grant: Close

A New Therapeutic Vaccine for HIV/AIDS

Open Date: 2015-03-30

Close Date: 2016-03-29

Grant: Close

To Establish a Novel and Rapid Phenotypic HIV-1 Drug Resistance Testing System

Open Date: 2013-07-01

Close Date: 2015-06-30

Articles (20)

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2024

Collaborators (5)

Leigang Jin

Research Assistant Professor

The University of Hong Kong

HONG KONG

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Ming Yue

The University of Hong Kong

HONG KONG

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Lin Zhu

Research Assistant Professor

Hong Kong Baptist University

HONG KONG

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Zhiwu Tan

Assistant Professor

The Hong Kong Polytechnic University

HONG KONG

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Runhong Zhou

Assistant Professor

The University of Hong Kong

HONG KONG

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Zhiwei Chen

Research Interests

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Recent Grants

Articles (20)

FGF21 synergizes with leptin to counteract obesity-related metabolic comorbidities by reversing hepatic leptin resistance

Glucagon-like peptide-1 receptor agonist prevents pulmonary fibrosis following acute COVID-19 infection associated with type 2 diabetes

Broad and durable protection against SARS-CoV-2 and SARS-CoV by an intranasal chimpanzee adenovirus vaccine expressing tandem RBDs and nucleocapsid

Sialic acid-anchored haemagglutinin stalk neutralizing antibody M-SiaB enhances protection against highly pathogenic influenza H5N1/Texas/2024

Human angiotensin‑converting enzyme 2‑specific benzothiazole-based allosteric inhibitor against pan‑sarbecoviruses

Nicotinamide mononucleotide enhances anti-tumor effect by resetting macrophages toward the inflammatory M1-like phenotype

Isoformic PD-1 impedes B cell activation and function in HIV-1 infection.

Cytokine profiling in COVID-19 patients by using ion mobility-mass spectrometry-based parallel reaction monitoring

Organoid-based neutralization assays reveal a distinctive profile of SARS-CoV-2 antibodies and recapitulate the real-world efficacy

BRD9 functions as an HIV-1 latency regulatory factor

An open-label study on the safety and immunogenicity of a PD-1-enhanced DNA vaccine used as a T cell booster for COVID-19

Grand Challenges on HIV/AIDS in China – The 5th Symposium, Yunnan 2024

Pandemic research: the need for a paradigm shift

A Prime-Boost Vaccination Approach Induces Lung Resident Memory CD8+ T Cells Derived from Central Memory T Cells That Prevent Tumor Lung Metastasis

Enhancing the efficacy of vaccinia-based oncolytic virotherapy by inhibiting CXCR2-mediated MDSC trafficking

Comprehensive Glycomic and Glycoproteomic Analyses of Human Programmed Cell Death Protein 1 Extracellular Domain

Super broad and protective nanobodies against Sarbecoviruses including SARS-CoV-1 and the divergent SARS-CoV-2 subvariant KP.3.1.1

Ultrapotent class I neutralizing antibodies post Omicron breakthrough infection overcome broad SARS-CoV-2 escape variants

Conditional splicing system for tight control of viral overlapping genes

Immune correlates with disease severity in older patients after SARS-CoV-2 BA.2 infection in Hong Kong

Collaborators (5)

Leigang Jin

Ming Yue

Lin Zhu

Zhiwu Tan

Runhong Zhou

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