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Zhongli Cai

Senior Research Associate

University of Toronto

Canada

Research Interests

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Professors in Canada

Articles (14)

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2026

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2025

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2023

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2023

Collaborators (7)

Philip Blower

King’s College London

UNITED KINGDOM

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Vincenzo Abbate

King’s College London

UNITED KINGDOM

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Miffy Cheng

Assistant Professor

The University of British Columbia

CANADA

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Stephane Angers

University of Toronto

CANADA

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Raymond M. Reilly

University of Toronto

CANADA

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Samantha Terry

Professor in Radiobiology

King’s College London

UNITED KINGDOM

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Mitchell Winnik

Professor

University of Toronto

CANADA

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Zhongli Cai

Research Interests

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Articles (14)

Bifunctional sulfur-rich macrocyclic chelators and their immunoconjugates for the targeted delivery of theranostic mercury-197

Preclinical Comparison of [111In]In- and [225Ac]Ac-DOTA-Trastuzumab IgG, F(ab′)2 and Fab for Theranostic SPECT/CT Imaging and α-Particle Radioimmunotherapy of HER2-Positive Human Breast Cancer

Auger electron-emitting EGFR-targeted and non-targeted [<SUP>197</SUP>Hg]Hg-gold nanoparticles for treatment of glioblastoma multiforme (GBM)

Convection-enhanced delivery of [<SUP>177</SUP>Lu]Lu-labeled gold nanoparticles combined with anti-PD1 checkpoint immunotherapy improves the survival of immunocompetent C57BL/6J mice with orthotopic GL261 murine glioma tumors

Progress towards Production and Application of <SUP>197(m/g)</SUP>Hg for Targeted Auger Electron Therapy (TAET)

Radiopharmaceutical kit to prepare Copper-64 labelled porphyrin-lipid nanoparticles for radiotracer imaging studies in cancer patients

Synthesis and characterisation of thallium-texaphyrin nanoparticles and their assessment as potential delivery systems for Auger electron-emitting 201Tl to cancer cells.

Bispecific radioimmunoconjugates exploit receptor heterogeneity for positron emission tomography of tumors expressing HER2 and/or EGFR

Optimizing the therapeutic index of targeted α -particle radioimmuotherapy (TART) of HER2-positive breast cancer tumors in NRG mice with 225Ac-labeled trastuzumab

Radiation nanomedicines for cancer treatment: a scientific journey and view of the landscape

Treatment of Orthotopic U251 Human Glioblastoma Multiforme Tumors in NRG Mice by Convection-Enhanced Delivery of Gold Nanoparticles Labeled with the β-Particle-Emitting Radionuclide, 177Lu

Relative Biological Effectiveness (RBE) of [<sup>64</sup>Cu]Cu and [<sup>177</sup>Lu]Lu-NOTA-panitumumab F (ab')<inf>2</inf> radioimmunotherapeutic agents vs. γ-radiation for decreasing the clonogenic survival in vitro of human pancreatic ductal adenocarcinoma (PDAC) cells

Adjuvant Auger Electron-Emitting Radioimmunotherapy with [<SUP>111</SUP>In]In-DOTA-Panitumumab in a Mouse Model of Local Recurrence and Metastatic Progression of Human Triple-Negative Breast Cancer

[<SUP>225</SUP>Ac]Ac- and [<SUP>111</SUP>In]In-DOTA-trastuzumab theranostic pair: cellular dosimetry and cytotoxicity in vitro and tumour and normal tissue uptake in vivo in NRG mice with HER2-positive human breast cancer xenografts

Collaborators (7)

Philip Blower

Vincenzo Abbate

Miffy Cheng

Stephane Angers

Raymond M. Reilly

Samantha Terry

Mitchell Winnik

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