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Zirui Dong

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Assistant Lab Director (Bioinformatics)

The Chinese University of Hong Kong (CUHK)

Hong Kong

Research Interests

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Professors in Biochemistry

Recent Grants

Grant: Open

Deciphering Refractory Epilepsy: Uncovering Mosaicism and NonCoding Variants via Ultra-Deep Sequencing and AI-Driven Validation

Open Date: 2026-10-01

Close Date: 2027-02-01

Grant: Open

The Mosaic Brain: towards a new understanding of focal epilepsies

Open Date: 2026-09-01

Close Date: 2028-03-01

Grant: Open

Unlocking the Non-Coding Genome: Development of A Phenotype-Driven and Cell-type Specific Analytical Pipeline to Decipher Expression Regulatory Defects underlying Idiopathic Fetal Anomalies

Open Date: 2026-06-01

Close Date: 2027-05-01

Grant: Open

Identification of Women at Risk for Premature Ovarian Insufficiency Using AI-Driven Facial Phenotyping

Open Date: 2026-01-01

Close Date: 2027-12-01

Grant: Open

Research on the Mechanism of Phenotypic Variation and Intervention Strategies of Chromosomal Microdeletion/Microduplication Syndrome

Open Date: 2025-09-01

Close Date: 2028-08-01

Articles (20)

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Collaborators (8)

Liona C Poon

Professor (Clinical)

The Chinese University of Hong Kong (CUHK)

HONG KONG

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Xiaoyan Chen

The Chinese University of Hong Kong (CUHK)

HONG KONG

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Paula Jorge

Auxiliary Professor

University of Porto

PORTUGAL

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Ge Lin

Professor

The Chinese University of Hong Kong (CUHK)

HONG KONG

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Mark Kilby

Co-Chairperson

University of Birmingham

UNITED KINGDOM

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Kwong Wai Choy

Professor

The Chinese University of Hong Kong (CUHK)

HONG KONG

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Fionnuala Mone

The Queen's University Belfast

UNITED KINGDOM

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Matthew Hoi Kin Chau

Research Assistant Professor

The Chinese University of Hong Kong (CUHK)

CHINA

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ApplyKite TwinLearns as you apply

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Zirui Dong

Research Interests

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Recent Grants

Articles (20)

Global recommendations for the use of diagnostic genomic sequencing in the prenatal setting on behalf of the ESHG and ISPD

Prenatal-Onset Recessive Titinopathies: Clinical Spectrum, Genotype–Phenotype Correlations, and Outcomes

Prenatal Tympanic Ring Anomaly Without Microtia: A Subtle Clue Toward Severe Early‐Onset Monogenic Disorders

NONO‐Related Syndromic X‐Linked Developmental Disability 34: Further Clinical and Molecular Delineation in a Prenatal Cohort

Clinical validation of artificial intelligence-assisted karyotyping on peripheral blood in a cytogenetic diagnostic laboratory

3D visualization of uterus and ovary: tissue clearing techniques and biomedical applications

Genomic Detection and Delineation of Chromoanasynthesis by Mate-Pair Sequencing

Mate-Pair Sequencing Enables Identification and Delineation of Balanced and Unbalanced Structural Variants in Prenatal Cytogenomic Diagnostics

TEDD 2.0: an advanced temporal gene expression database enabled by in-silico functional analyses for developmental mechanism investigation

Contribution of Genomic Imbalance in Prenatal Congenital Anomalies of the Kidney and Urinary Tract: A Multi‐Center Cohort Study

Detection of genomic variants by genome sequencing in foetuses with central nervous system abnormalities

Genome sequencing in the prenatal diagnosis of structural malformations in the fetus

Identification of cryptic balanced translocations in couples with unexplained recurrent pregnancy loss based upon embryonic PGT-A results

Incremental Yield of Whole-Genome Sequencing Over Chromosomal Microarray Analysis and Exome Sequencing for Congenital Anomalies in Prenatal Period and Infancy: Systematic Review and Meta-analysis

Prenatal diagnosis of polycystic kidney caused by biallelic hypomorphic variants in the PKD1 gene

Incremental yield of whole genome sequencing over chromosome microarray and exome sequencing for congenital anomalies in prenatal period and infancy: systematic review and meta‐analysis

A pilot investigation of low-pass genome sequencing identifying site-specific variation in chromosomal mosaicisms by a multiple site sampling approach in first-trimester miscarriages

Single-cell analysis reveals specific neuronal transition during mouse corticogenesis.

Fertility preservation in pediatric healthcare: a review.

Low-Pass Genome Sequencing-Based Detection of Paternity: Validation in Clinical Cytogenetics

Collaborators (8)

Liona C Poon

Xiaoyan Chen

Paula Jorge

Ge Lin

Mark Kilby

Kwong Wai Choy

Fionnuala Mone

Matthew Hoi Kin Chau

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