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Technical University of Denmark

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PhD scholarship in 3D Cochlear Histopathology in Ageing and Systemic Disease - DTU Health Tech Technical University of Denmark in Denmark

Degree Level

PhD

Field of study

Computer Science

Funding

3-year PhD scholarship; salary and appointment terms follow the collective agreement with the Danish Confederation of Professional Associations.

Deadline

Nov 25, 2026

Country flag

Country

Denmark

University

Technical University of Denmark

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Keywords

Computer Science
Biomedical Engineering
Biology
Metabolic Syndrome
Aging
Alzheimer's Disease
Neuropsychology
Medical Science
Auditory Neuroscience
Hearing Loss
Statistics
Systemic Diseases

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About this position

This PhD scholarship at DTU Health Tech focuses on understanding how cochlear vascular and sensorineural pathology develops and changes in ageing and systemic disease. The project studies the cochlea in healthy ageing and in age-related conditions such as dementia and metabolic syndrome, using rodent models to connect tissue-level changes with auditory function and broader disease markers.

The research is method-driven and centred on the development of preclinical immunolabelling, tissue clearing, and light-sheet fluorescence microscopy workflows for intact cochleae. A major part of the project is to generate 3D imaging datasets and then build quantitative image-analysis approaches that can reveal spatial and temporal relationships between vascular and sensorineural pathology. The outcomes are intended to improve understanding of hearing loss pathogenesis and support future evaluation of therapeutic responses.

The student will join the Centre for Auditory Neuroscience in the Hearing Systems section at DTU Health Tech, an interdisciplinary environment supported by the William Demant Foundation. The team brings together neurobiologists, cognitive neuroscientists, acousticians, computer scientists, and medical doctors, with opportunities to collaborate with preclinical and clinical scientists inside and outside Denmark.

The project involves experimental work in rodent models, development and validation of tissue protocols, acquisition of microscopy data from intact cochleae, and contribution to image-analysis pipeline development. The student will also publish papers, present at international conferences, and take part in teaching and supervision at DTU. The position includes PhD coursework and a research stay at a partner laboratory.

Funding details

3-year PhD scholarship; salary and appointment terms follow the collective agreement with the Danish Confederation of Professional Associations.

What's required

Applicants must have a two-year master’s degree (120 ECTS points) or equivalent academic level in neuroscience, medicine, biomedicine, veterinary medicine, biomedical engineering, molecular biology, or a related field. Required experience includes hands-on work with laboratory rodents in a research setting, practical immunofluorescent tissue labelling and tissue-processing optimization, fluorescence microscopy acquisition and evaluation, and quantitative analysis through scripting, image analysis, or statistics. Applicants should show a strong interest in inner-ear pathology, the ability to formulate and pursue research questions independently, meticulous handling of delicate preparations, rigorous documentation of protocols, strong written and spoken English, and the ability to work in a collaborative interdisciplinary environment. Familiarity with the auditory system or inner-ear biology, and prior experience with tissue clearing, light-sheet microscopy, or image analysis, is an advantage.

How to apply

Submit the complete online application through the 'Apply now' link by 25 November 2026 at 23:59 Danish time. Upload all materials as one PDF in English, including a cover letter, CV, transcripts, and BSc/MSc diploma with grading scale description. Recommendation letters up to two are welcome but not required.

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