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Roeland Lameris

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Arts-onderzoeker PhD Medische Oncologie Amsterdam UMC in Netherlands

Degree Level

PhD

Field of study

Oncology

Funding

Paid PhD position with salary scale 10: €3,724 to €5,867 gross per month for a full-time appointment, plus 8.3% year-end bonus, holiday allowance, pension, and travel reimbursement.

Deadline

Nov 20, 2026

Country flag

Country

Netherlands

University

Amsterdam UMC

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Keywords

Oncology
Immunotherapy
Hematology
Biology
Tumor Immunology
Myelodysplastic Syndrome
Spatial Transcriptomic

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About this position

This PhD position at Amsterdam UMC sits at the intersection of medical oncology, hematology, immunology, and early-phase clinical research. The project focuses on improving cancer immunotherapy through two phase I studies, bringing together clinical trial work and laboratory-based translational research in a multidisciplinary setting.

The first study investigates whether an existing hematological drug can safely enhance the effectiveness of immunotherapy in solid tumours. The second study examines the safety and biological effects of a bispecific T-cell engager developed in the lab for patients with myelodysplastic syndrome. Together, these studies aim to translate preclinical insights into clinical applications for patients with solid and hematological malignancies.

You will work within the Cancer Center Amsterdam and the Amsterdam Immunity & Infection Institute, alongside a young and enthusiastic team with expertise spanning tumour immunology, immunotherapy, and cancer research from preclinical to clinical stages. The project also connects closely with the Immunotherapy Lab of the Department of Medical Oncology, where work on tumour-mediated immune suppression, myeloid cells as therapeutic targets, local immune activation in tumour-draining lymph nodes, and bispecific antibodies supports the broader research environment.

As the PhD researcher, you will coordinate the two phase I studies, contribute to patient inclusion and follow-up, and analyse clinical as well as immunological data. In parallel, you will perform translational laboratory research using blood and tumour biopsies, with methods including flow cytometry and spatial transcriptomics. The project offers exposure to both patient-facing research and advanced immune monitoring in a strong academic medical centre.

Funding details

Paid PhD position with salary scale 10: €3,724 to €5,867 gross per month for a full-time appointment, plus 8.3% year-end bonus, holiday allowance, pension, and travel reimbursement.

What's required

A (nearly) completed medical degree is required. Applicants should have an affinity with immunology and cancer research, excellent written and spoken communication skills in Dutch and English, and preferably experience in oncological patient care and scientific laboratory research. Experience with SPSS, R, or similar software is a plus. Candidates should be motivated, disciplined, and able to work in a multidisciplinary environment combining clinical work, laboratory research, and patient care.

How to apply

Apply online via the AcademicTransfer application link. Submit a CV, motivation letter, and contact details for preferably two referees. Selection may include an assessment, interviews, and a presentation in a second round.

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Professors

Prof. at Amsterdam UMC

University Name
Country flag

Netherlands

Research Interests

Hematology

Immunotherapy

Spatial Transcriptomic

Tumor Immunology

Biology

Prof. at Amsterdam UMC

University Name
Country flag

Netherlands

Research Interests

Spatial Transcriptomic

Hematology

Oncology

Tumor Immunology

Biology